Subjects used to calculate pregnancy-specific reference intervals must exclude those who are overweight or obese
Annals of Clinical Biochemistry, Volume 60, Issue 4, Page 291-291, July 2023.
Journal
EDTA plasma in glass and polyethylene terephthalate tubes is suitable for measurement of B-type natriuretic peptide on the Mindray CL-6000i
Annals of Clinical Biochemistry, Ahead of Print. AimsTo explore differences in B-type natriuretic peptide (BNP) concentration and stability and evaluate BNP accuracy in different collection tubes.MethodsBNP concentrations in heparin/glass, EDTA/glass, …
An observational study of replicate faecal immunochemical tests in the urgently referred symptomatic cohort
Annals of Clinical Biochemistry, Ahead of Print. IntroductionTriage of patients with suspected colorectal cancer (CRC) utilises a single faecal immunochemical test (FIT) at a defined threshold. Limited evidence exists regarding whether replicate FIT im…
Falsely elevated thyroid hormone levels associated with fibrin interference in patients receiving oral anticoagulant therapy
Annals of Clinical Biochemistry, Volume 60, Issue 4, Page 249-258, July 2023. ObjectiveUnique clinical courses were observed in two asymptomatic patients receiving warfarin who referred to our hospital because of suspected central hyperthyroidism. We e…
Fibrin monomer complex as a potential thrombosis marker related to venous thromboembolism risk in pregnant women
Annals of Clinical Biochemistry, Volume 60, Issue 4, Page 279-285, July 2023. BackgroundPregnancy is a risk factor for venous thromboembolism (VTE) due to increased coagulation factor activity and decreased protein S activity. However, thrombosis marke…
The effectiveness of an automated algorithm as a tool for investigating the cause of anaemia in undiagnosed patients from general practitioners
Annals of Clinical Biochemistry, Volume 60, Issue 4, Page 270-278, July 2023. BackgroundThe Dutch guideline algorithm for the analysis of anaemia in patients of general practitioners (GPs) was programmed in a Clinical Decision Support system (CDS-anaem…
Hepcidin analysis in pneumonia: Comparison of immunoassay and LC-MS/MS
Annals of Clinical Biochemistry, Ahead of Print. BackgroundThe iron-regulatory hormone hepcidin is a promising biomarker to differentiate anaemia of inflammation from iron deficiency. Plasma hepcidin concentrations increase substantially during inflamm…
The laboratory investigation of pleural fluids: An update based on the available evidence
Annals of Clinical Biochemistry, Volume 60, Issue 4, Page 228-235, July 2023. Selecting appropriate laboratory tests based on available evidence is central to improve clinical effectiveness and impacting on patient outcome. Although long studied, there…
Testing for lactase non-persistence in a Dutch population: Genotyping versus the hydrogen breath test
Annals of Clinical Biochemistry, Volume 60, Issue 4, Page 243-248, July 2023. BackgroundLactose intolerance is defined as the presence of gastrointestinal symptoms, such as bloating, abdominal pain or diarrhoea, after consumption of lactose in individu…
Comparison of faecal calprotectin using two collection and extraction strategies for the BÜHLMANN CALEX® Cap – possible implications for clinical cut-offs?
Annals of Clinical Biochemistry, Volume 60, Issue 4, Page 236-242, July 2023. BackgroundFaecal calprotectin has been identified as a useful biochemical marker in the differentiation of inflammatory bowel disease and irritable bowel syndrome. Typically,…