Journal
Practical approaches to the detection of macrotroponin
Annals of Clinical Biochemistry, Ahead of Print. IntroductionMacrotroponin is increasingly recognised as a cause of confusion in interpreting high-sensitivity cardiac troponin (hs-cTnI) results. In this study, we sought to evaluate two practical approa…
Biomarkers of endometriosis
Endometriosis is one of the most severe female reproductive disorders, affecting 6–10% of women between 18 and 35. It is a gynaecological condition where endometrial tissue develops and settles outside the uterus. The aetiology of endometriosis is primarily influenced by genetic, epigenetic, and non-genetic variables, making it highly challenging to create a therapeutic therapy explicitly … Read more
Preliminary evaluation of the diagnostic performance of Roche Elecsys® active vitamin B12 versus total vitamin B12 for vitamin B12 deficiency screening
Annals of Clinical Biochemistry, Ahead of Print. IntroductionThe prevalence of vitamin B12 deficiency is high in at-risk populations with sometimes irreversible consequences. Beside total B12 (TVB12), active B12 (AVB12) is a promising first-line marker…
Current practice and recommendations for managing transgender patient data in clinical laboratories in the United Kingdom and Republic of Ireland
Annals of Clinical Biochemistry, Ahead of Print. BackgroundTransgender people may avoid seeking medical care due to previous negative experiences and fear of discrimination. Clinical laboratories can contribute to a poor patient experience and clinical…
Development of blood collection tubes for glucose measurement using adenosine 3-phosphate and sodium fluoride as glycolytic inhibitors
Annals of Clinical Biochemistry, Ahead of Print. BackgroundBlood collection tubes with sodium fluoride (NaF) added as a glycolytic inhibitor are widely used for glucose measurement. However, the glycolytic inhibitory effects of NaF are insufficient, an…
UKMedLab2023 conference – A celebration of 70 years of the ACB
Annals of Clinical Biochemistry, Ahead of Print.
Use of finer needles for venipuncture increases in vitro haemolysis despite reducing persistent pain and nerve injury: A retrospective study
Annals of Clinical Biochemistry, Ahead of Print. BackgroundAlthough venipuncture is minimally invasive, and is the most frequently performed medical procedure, it carries the small risk of causing persistent pain, including nerve damage. Recently, our …