Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis
Key Points Question When does neuroaxonal pathology occur in people with multiple sclerosis (MS) who experience disability worsening? Findings In this cohort study including 1899 individuals, serum neurofilament light chain elevation, as a sign of accelerated neuroaxonal injury, was detected approximately 1 year preceding disability worsening events associated with relapses and 1 to 2 years before worsening … Read more