Season of sampling and the interpretation of serum homocysteine results: a within-person analysis of 268,877 health-screening examinationsSeung-Hwan Kimon September 22, 2026 at 10:00 am

Clin Chem Lab Med. 2026 Sep 23. doi: 10.1515/cclm-2026-1304. Online ahead of print. ABSTRACT OBJECTIVES: Serum total homocysteine (tHcy) is interpreted against fixed reference intervals and a decision limit. Whether the month of blood collection is a material source of variation, and whether it reflects the seasonal cycle of 25-hydroxyvitamin D [25(OH)D], is unresolved because … Read more

Thyroglobulin antibody in differentiated thyroid cancer: international laboratory practice survey and the case for a dual-threshold modelEliane F E Wenstedton September 21, 2026 at 10:00 am

Clin Chem Lab Med. 2026 Sep 21. doi: 10.1515/cclm-2026-1063. Online ahead of print. ABSTRACT OBJECTIVES: Anti-thyroglobulin antibodies (TgAb) have a dual role during the follow-up of differentiated thyroid cancer (DTC): they may interfere with thyroglobulin (Tg) immunoassays and also serve as surrogate biomarkers of disease status. However, laboratory practices for TgAb measurement and reporting remain … Read more

Responsibility without a map: defining oversight of automated result release in the medical laboratorySaid İnciron September 21, 2026 at 10:00 am

Clin Chem Lab Med. 2026 Sep 21. doi: 10.1515/cclm-2026-1371. Online ahead of print. ABSTRACT Laboratory specialists have been assigned responsibility for algorithmically assisted reporting without an operational definition of what responsible oversight means. Results pass largely through rule-based approval systems, and increasingly through probabilistic models, yet the obligation attached to the specialist’s name on the … Read more

Delivering the EU Safe Hearts Plan: the essential role of laboratory medicine in cardiovascular healthDamien Grusonon September 20, 2026 at 10:00 am

Clin Chem Lab Med. 2026 Sep 21. doi: 10.1515/cclm-2026-1439. Online ahead of print. ABSTRACT The European Union Safe Hearts Plan provides an opportunity to strengthen cardiovascular prevention, early detection, treatment, and monitoring across Europe. This EFLM position paper argues that laboratory medicine must be recognized as a central component of its implementation. Reliable and harmonized … Read more

Filling the gaps in high-priority reference materials for implementing metrological traceability in laboratory medicineMauro Panteghinion September 19, 2026 at 10:00 am

Clin Chem Lab Med. 2026 Sep 21. doi: 10.1515/cclm-2026-1332. Online ahead of print. ABSTRACT The global harmonization of measurements in laboratory medicine is facilitated by the development and implementation of reference measurement systems, including suitable certified reference materials (CRMs). There are, however, a relatively small number of CRM producers worldwide. In the context of limited … Read more

Availability and characteristics of external quality assessment (EQA) schemes for measurement of hemolysis, icterus and lipemia (HIL) in routine coagulation testing, a collaborative study from the European Organisation for External Quality Assurance in Laboratory Medicine (EQALM)Ann Helen Kristoffersenon September 18, 2026 at 10:00 am

Clin Chem Lab Med. 2026 Sep 21. doi: 10.1515/cclm-2026-1130. Online ahead of print. NO ABSTRACT PMID:42758902 | DOI:10.1515/cclm-2026-1130

Digital and computational morphology in hematology: current platforms, clinical evidence, and future requirementsGina Zinion September 13, 2026 at 10:00 am

Clin Chem Lab Med. 2026 Sep 14. doi: 10.1515/cclm-2026-1265. Online ahead of print. ABSTRACT INTRODUCTION: Morphologic examination of peripheral blood and bone marrow remains central to the diagnosis and classification of hematologic disorders. Conventional optical microscopy, however, is labor-intensive, dependent on operator expertise, and affected by interobserver variability. Digital morphology has developed from automated image … Read more

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