Advanced Laboratory Medicine

Real-time immunophenotypic shifts in pediatric B lymphoblastic leukemia providing implications for minimal residual disease detection​Omer Javedon September 22, 2025 at 10:00 am

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Adv Lab Med. 2025 May 5;6(3):358-364. doi: 10.1515/almed-2024-0202. eCollection 2025 Sep. ABSTRACT OBJECTIVES: Disease monitoring in acute leukemia management is crucial for risk stratification and chemotherapy response assessment. Minimal residual disease (MRD) testing is the most reliable tool, measuring antigenic expression differences between leukemic cells, hematogones, and mature benign B-cells. Modulation of antigen expression during … Read more

Use of external quality assessment in extra-analytical phases in clinical laboratories in Spain: a survey by the Spanish Society of Laboratory Medicine (SEQCML)​Andrea Caballero Garraldaon May 29, 2025 at 10:00 am

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Adv Lab Med. 2025 Apr 21;6(2):199-205. doi: 10.1515/almed-2025-0067. eCollection 2025 Jun. ABSTRACT OBJECTIVES: Quality indicators (QIs) are a valuable tool for monitoring and improving extra-analytical phase performance in the clinical laboratory (CL). For that reason, the Spanish Society of Laboratory Medicine (SEQCML) launched its Pre-analytical Phase EQA Program in 2001. METHODS: In 2023, a survey … Read more

Uso de la evaluación externa de la calidad en las fases extraanalíticas de los laboratorios clínicos españoles: una encuesta de la Sociedad Española de Medicina de Laboratorio (SEQCML)​Andrea Caballero Garraldaon May 29, 2025 at 10:00 am

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Adv Lab Med. 2025 Apr 3;6(2):206-212. doi: 10.1515/almed-2024-0160. eCollection 2025 Jun. NO ABSTRACT PMID:40438560 | PMC:PMC12107416 | DOI:10.1515/almed-2024-0160

How to handle lipemic CBC samples on Sysmex hematology analyzers?​Vanja Radišić Biljakon May 29, 2025 at 10:00 am

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Adv Lab Med. 2025 Mar 20;6(2):166-172. doi: 10.1515/almed-2024-0206. eCollection 2025 Jun. ABSTRACT OBJECTIVES: Lipemia poses a significant preanalytical problem for complete blood count (CBC) measurement due to limited and non-standardized methods for recognition and removal. We aimed to verify the optical hemoglobin (Hb-O) measurements on the Sysmex XN-1000 hematology analyzer (HA) as a possible reliable … Read more

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