Addressing the silent epidemic of recreational nitrous oxide use: a position, call to action and recommendations by the European Federation of Clinical Chemistry and Laboratory Medicine Committee on Biological Markers of Nitrous Oxide AbuseGuillaume Grzychon November 26, 2025 at 11:00 am

Clin Chem Lab Med. 2025 Nov 20. doi: 10.1515/cclm-2025-1060. Online ahead of print. ABSTRACT Recreational nitrous oxide (N2O) use has emerged as a growing public health concern, with increasing reports of neurological, psychiatric, and thrombotic complications. This position paper from the EFLM Committee on Biological Markers of Nitrous Oxide Abuse highlights the urgent need for … Read more

Performance evaluation of a new high-sensitivity cardiac troponin T assay: hs-cTnT (CLIA) assayXin Shuon November 25, 2025 at 11:00 am

Clin Chem Lab Med. 2025 Nov 26. doi: 10.1515/cclm-2025-1258. Online ahead of print. ABSTRACT OBJECTIVES: The Fourth Universal Definition of Myocardial Infarction recommends high-sensitivity cardiac troponin (hs-cTn) as the preferred biomarker for diagnosing myocardial infarction. This study evaluated the analytical and clinical performance of a novel hs-cTnT chemiluminescence immunoassay (CLIA) developed by Mindray. METHODS: Analytical … Read more

Analytical Imprecision and Therapeutic Intervals for Lithium – Are There Implications for Old Age Patients with Bipolar Disorder?​​on November 25, 2025 at 4:00 pm

Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Janet Zhou, Demitra Tsoukalas, Nethra Chittiprol, Peter Kavsak, Felix Leung, Jennifer Taher, Zahraa Ali-Mohammed, Saranya Arnoldo, Heather Tysick, Lei Fu, Sara A. Love, Rajeevan Selvaratnam

The automated clinical mass spectrometry revolution​on October 1, 2025 at 4:00 am

Join Professor Joe El Khoury as he discusses his three areas of research including the impact of sample quality on diagnostic accuracy, the urgency of early kidney injury detection, and the evolving role of mass spectrometry in clinical labs. Learn how DART technology can accelerate toxicology workflows and hear his perspective on automation, workforce challenges, … Read more

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