ccinfoadmin 
New tumor marker can detect gastric cancer with nearly 90% accuracy (medicalxpress.com) A research team led by the Nagoya University Graduate School of Medicine has discovered that the stromal cell-derived factor 4 (SDF-4) protein is a reliable cancer marker. As simple blood tests accurately detect the protein, their findings suggest the potential of the marker … Read more
Key Points Question When does neuroaxonal pathology occur in people with multiple sclerosis (MS) who experience disability worsening? Findings In this cohort study including 1899 individuals, serum neurofilament light chain elevation, as a sign of accelerated neuroaxonal injury, was detected approximately 1 year preceding disability worsening events associated with relapses and 1 to 2 years before worsening … Read more
A global blood test for concussion could be a step closer after a Monash University-led study discovered specific proteins or biomarkers that can help diagnose concussions relatively quickly and accurately. Once approved, a blood test identifying these biomarkers could improve the diagnostic process of concussion following accidents, sport-related collisions, or other injuries, aiding management and … Read more
Pauline Anderson September 27, 2023 TOPLINE: Perioperative myocardial injury, reflected by release of high-sensitivity cardiac troponin T, is associated with 30-day mortality after various cardiac surgeries at postoperative prognostic cutoffs higher than proposed in current definitions, new research suggests. METHODOLOGY: TAKEAWAY: IN PRACTICE: “These results provide important novel insights into the association of hs-cTnT with 30-day mortality … Read more
Guidance for Practicing Primary Care Linda Girgis, MDDISCLOSURES September 26, 2023 In the United States this year, approximately 288,300 men will be newly diagnosed with prostate cancer and about 34,700 men will die from this disease. It is the second leading cause of cancer in men, and one out of every eight men will be diagnosed with this cancer at some … Read more
Researchers have identified a mechanistic link between zinc levels in humans and the risk of type 2 diabetes and fatty liver disease. The research, published today as a Reviewed Preprint in eLife, is described by editors as a fundamental study that substantially advances our understanding of the role of zinc in metabolism. The researchers provide solid … Read more
by Aaron Wagner, Pennsylvania State University Sepsis is a life-threatening medical emergency that occurs when an infection causes a chain reaction throughout the body that can lead to the failure of multiple organs in rapid succession. In the United States about 350,000 people die from sepsis each year, according to the Centers for Disease Control and … Read more
Volume 83, Issue 7, November 2023, Page 444-447.
To investigate the regulation of soluble very low-density lipoprotein receptor (sVLDL-R), which is cleaved mostly from the extracellular domain of VLDL-R II, we generated two rat monoclonal antibodies (mAbs) against human sVLDL-R, and used them to develop a sandwich enzyme-linked immunosorbent assay (ELISA) to measure sVLDL-R levels in human serum or plasma. The ELISA had … Read more
Introduction Urinalysis is essential for diagnosing kidney-related medical conditions. Urine test strip analysis serves as an initial and efficient screening method for reflex testing with accurate quantitative methods. Materials and Methods Freshly voided urines (n=206) were analysed using two urine test strip brands on UC-MAX (Menarini) and cobas u 601 (Roche Diagnostics) instruments. Ordinal scale … Read more
