ccinfoadmin – Page 13 – Clinical Chemistry INFO

Utility of flow cytometric PAX5 protein detection for the diagnosis of B-cell acute lymphoblastic leukemiaTanintorn Pootrakulon January 27, 2026 at 11:00 am

January 27, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Jan 28. doi: 10.1515/cclm-2025-1647. Online ahead of print. ABSTRACT OBJECTIVES: Accurate B-lineage assignment in acute leukemia is critical for therapeutic decisions. While nuclear expression of PAX5 protein (nPAX5) is a highly reliable marker for B-cell differentiation, its conventional assessment by time-consuming immunohistochemistry (IHC) is not ideal for rapid diagnosis. This … Read more

Cardiac troponin T measurement following cardiac surgery in children with congenital heart defects predicts adverse outcomesGiuseppe Isgròon January 27, 2026 at 11:00 am

January 27, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Jan 28. doi: 10.1515/cclm-2025-1461. Online ahead of print. ABSTRACT OBJECTIVES: Testing for high-sensitivity cardiac troponin (hs-cTn) often occurs following pediatric cardiac surgery, although evidence regarding its utility remains heterogeneous. This study aimed to assess the prognostic value of postoperative hs-cTnT patterns detected within 48 h after cardiac surgery. METHODS: Serum … Read more

Fibroblast growth factor 23-induced hypophosphatemia in a malignant phosphaturic mesenchymal tumor: presentation of a rare caseon January 26, 2026 at 3:52 pm

January 26, 2026 by ccinfoadmin

Publication date: Available online 25 January 2026 Source: Clinical Biochemistry Author(s): Diver Alexis Chicangana Tuquerres, Andrés David Sastre Martinez, Carlos Mário Barrios Herrera, Paula Andrea Torres Pérez, Carlos Fernando Acuña Roldán, Gabriel Jaime Varela Aguirre, Andres Felipe García Ramos

WITHDRAWN: A novel digital PCR assay targeting major BCR::ABL1 fusion transcriptson January 26, 2026 at 12:42 pm

January 26, 2026 by ccinfoadmin

Publication date: Available online 19 August 2023 Source: Practical Laboratory Medicine Author(s): Soo Jung Lee, Jong-Mi Lee, Ari Ahn, Sung-Eun Lee, Yuna Hong, Gun Dong Lee, Hyun-Woo Song, Min-Sik Song, Seung-Shick Shin, Myungshin Kim, Yonggoo Kim

The CDKN2A/B rs10811661 polymorphism is associated with metabolic syndrome, insulin resistance, and lipid levels in individuals with obesity and impaired fasting glucoseon January 25, 2026 at 2:32 pm

January 25, 2026 by ccinfoadmin

Publication date: Available online 24 January 2026 Source: Clinical Biochemistry Author(s): Daniel de Luis, Olatz Izaola, David Primo

Clinical Labs: Working with planetary health for patient healthon January 25, 2026 at 2:32 pm

January 25, 2026 by ccinfoadmin

Publication date: Available online 24 January 2026 Source: Clinical Biochemistry Author(s): Andre Mattman, Janet Simons

Analytical performance evaluation and reference limits establishment of a new chemiluminescence growth stimulation expressed Gene 2 Assayon January 25, 2026 at 12:26 pm

January 25, 2026 by ccinfoadmin

Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Litao Zhang, Chenbin Zhang, Xin Shu, Jiajia Zhu, Hui Wang, Ting Deng, Yisha Jing, Haiyan Liu, Zhenlu Zhang

An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 5-alpha-dihydrotestosterone in human serum and plasmaLea Lewinon January 24, 2026 at 11:00 am

January 24, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Jan 26. doi: 10.1515/cclm-2025-1155. Online ahead of print. ABSTRACT OBJECTIVES: 5α-dihydrotestosterone (DHT) is a potent androgen, related to male sexual development and irreversibly synthesized from testosterone via 5α-reductase. Dysfunctions in the 5α-reductase system, locally or globally, can have substantial health impacts; measurement of both DHT levels and the testosterone-DHT ratio … Read more

Validating CALIPER pediatric reference intervals in a U.S. population using retrospective outpatient data and RefineRon January 24, 2026 at 5:32 pm

January 24, 2026 by ccinfoadmin

Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Jillian Kodger, Thomas J.S. Durant, Nalan Yurtsever, Joe M. El-Khoury

Biological variation and inter-relation between key calcium homeostasis biomarkersNora Alicia Guldhaugon January 23, 2026 at 11:00 am

January 23, 2026 by ccinfoadmin

Clin Chem Lab Med. 2026 Jan 26. doi: 10.1515/cclm-2025-1225. Online ahead of print. ABSTRACT OBJECTIVES: This study aims to explore the biological variability of calcium homeostasis biomarkers, including calcium, phosphate, magnesium, 25-OH vitamin D, 1,25-OH vitamin D, and parathyroid hormone (PTH), and to develop a model that predicts PTH concentrations based on these parameters. METHODS: … Read more