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Researchers identify circulating proteins linked to preeclampsia and other hypertensive disorders of pregnancy

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Preeclampsia and other hypertensive disorders of pregnancy—which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy—carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited. A team led by researchers at Massachusetts General Hospital (MGH) and the … Read more

New tumor marker can detect gastric cancer with nearly 90% accuracy

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New tumor marker can detect gastric cancer with nearly 90% accuracy (medicalxpress.com) A research team led by the Nagoya University Graduate School of Medicine has discovered that the stromal cell-derived factor 4 (SDF-4) protein is a reliable cancer marker. As simple blood tests accurately detect the protein, their findings suggest the potential of the marker … Read more

Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis

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Key Points Question  When does neuroaxonal pathology occur in people with multiple sclerosis (MS) who experience disability worsening? Findings  In this cohort study including 1899 individuals, serum neurofilament light chain elevation, as a sign of accelerated neuroaxonal injury, was detected approximately 1 year preceding disability worsening events associated with relapses and 1 to 2 years before worsening … Read more

New blood test could improve concussion diagnosis: Study

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A global blood test for concussion could be a step closer after a Monash University-led study discovered specific proteins or biomarkers that can help diagnose concussions relatively quickly and accurately. Once approved, a blood test identifying these biomarkers could improve the diagnostic process of concussion following accidents, sport-related collisions, or other injuries, aiding management and … Read more

Cardiac Troponin Predicts Mortality Post Surgery

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Pauline Anderson September 27, 2023 TOPLINE: Perioperative myocardial injury, reflected by release of high-sensitivity cardiac troponin T, is associated with 30-day mortality after various cardiac surgeries at postoperative prognostic cutoffs higher than proposed in current definitions, new research suggests. METHODOLOGY: TAKEAWAY: IN PRACTICE: “These results provide important novel insights into the association of hs-cTnT with 30-day mortality … Read more

Prostate Cancer Screening Guidelines: To PSA or Not to PSA

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Guidance for Practicing Primary Care Linda Girgis, MDDISCLOSURES  September 26, 2023 In the United States this year, approximately 288,300 men will be newly diagnosed with prostate cancer and about 34,700 men will die from this disease. It is the second leading cause of cancer in men, and one out of every eight men will be diagnosed with this cancer at some … Read more

Scientists reveal mechanistic link between zinc levels and diabetes

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Researchers have identified a mechanistic link between zinc levels in humans and the risk of type 2 diabetes and fatty liver disease. The research, published today as a Reviewed Preprint in eLife, is described by editors as a fundamental study that substantially advances our understanding of the role of zinc in metabolism. The researchers provide solid … Read more

New test for sepsis could save lives in emergency departments, study suggests

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by Aaron Wagner, Pennsylvania State University Sepsis is a life-threatening medical emergency that occurs when an infection causes a chain reaction throughout the body that can lead to the failure of multiple organs in rapid succession. In the United States about 350,000 people die from sepsis each year, according to the Centers for Disease Control and … Read more

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