Clin Chem. 2025 Dec 30;72(1):39-46. doi: 10.1093/clinchem/hvaf146.
ABSTRACT
BACKGROUND: Persistent disparities in prenatal care contribute to preventable maternal and fetal morbidity and mortality, particularly among high-risk and underserved populations. Clinical laboratories play a central role in early detection of prenatal gaps in care and stratifying pregnancy-related risk factors linked to other health conditions, yet their full potential remains underutilized.
CONTENT: This review examines the integration of data analytics with laboratory information systems and electronic health records to proactively identify and address lapses in prenatal care. Structured laboratory data can drive clinical decision support, stratify risk in early pregnancy, and guide targeted interventions. Predictive analytics and population health tools are discussed as mechanisms to uncover disparities in access, optimize resource allocation, and inform system-level strategies. While there are critical challenges that must be addressed, including data interoperability, incomplete data sets, and ethical considerations such as patient autonomy and data privacy, data analytics can be leveraged to advance prenatal care.
SUMMARY: By centering diagnostic data within the broader analytics framework, clinical laboratories are positioned to lead multidisciplinary efforts to deliver more equitable and effective maternal healthcare.
PMID:41468133 | DOI:10.1093/clinchem/hvaf146