Multiplexed protease activity profiling for host response-based Sepsis diagnosison October 24, 2026 at 1:24 pm October 24, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Emily R. Caton, Yezhi Pan, Kiana M. Kiser, Caroline R. Haddaway, Wayne A. Bryden, Michael McLoughlin, Marek A. Mirski, Robert H. Christenson, Cindy C. Sevilla, Shuo Chen, Sheng Feng, Dapeng Chen
Capillary self-blood collection for centralized testing – a pan-European cross-sectional pilot studyon October 24, 2026 at 1:24 pm October 24, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Dominik Schröder, Louis Kuhnke, Linda Hoffmeister, Christopher Schuchardt, Eva Hummers, Georg M.N. Behrens, Andrea Stölting, Metodi Stankov, Alexandra Dopfer-Jablonka, Christine Happle, Frank Müller
Functional characterization of compound heterozygous HLCS variants reveals exon skipping and impaired biotin responsiveness in holocarboxylase synthetase deficiencyon October 23, 2026 at 12:55 pm October 23, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Jin-Kyu Kang, Eui-Jeon Woo, Sook-Za Kim, Haing-Woon Baik
Algorithm to detect IgA deficiency during automated tissue transglutaminase antibody testingon October 22, 2026 at 12:21 pm October 22, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Heikki Ilmavirta, Ulla Ristonmaa, Kalle Kurppa, Tuure Kinnunen
ThaCoder: an explainable deep learning framework for thalassemia screening using routine complete blood count: a multi-center validation studyon October 22, 2026 at 12:21 pm October 22, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Xiaosong Su, Yan Lin, Kouqiong Wang, Yuning Lin, Lin Wu, Xiang Jiang, Yi Shi, Baishen Pan, Beili Wang, Wei Guo, Jiaye Zhou
Familial glycerol kinase deficiency uncovered by triglyceride-lipemic index discordanceon October 21, 2026 at 11:44 am October 21, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Carla Fernández-Prendes, Álvaro Piedra-Aguilera, Andrea Ros, Alejandra Pérez-Itza, Analia Ramos, Sandra Bonache, Ignacio Blanco
Evaluation of external quality assessment results of 15 clinical laboratory quality indicators in China from 2019 to 2021on October 21, 2026 at 11:44 am October 21, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Yuxuan Du, Zhiguo Wang, Zhixin Zhang, Wei Wang, Jiali Liu, Jie Ma
Impact of temperature on hemoglobin stability in dried blood spots for newborn screening for sickle cell diseaseon October 18, 2026 at 9:20 am October 18, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): R. Rolla, M. Vidali, L. Giacomini, S. Sacchetti, U. Dianzani, M. Ammirabile, R. Paleari
A predictive model for optimizing kappa free light chain dilution in cerebrospinal fluid sampleson October 17, 2026 at 3:03 pm October 17, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Ana Turčić, Ljiljana Zaninović, Matko Čeme, Željka Vogrinc
Neudesin alterations in hypothyroidism with and without metabolic syndrome and type 2 diabetes: association with metabolic disturbances and potential biomarker valueon October 16, 2026 at 2:24 pm October 16, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Aliaa A. Razzak, Dhamyaa O. Shalgam, Noor T. Tahir, Ghassan M. Sulaiman, Hamdoon A. Mohammed
Machine learning-aided serum N-glycomic signatures reveal potential biomarkers for acute ischemic stroke and minocycline treatment responseon October 15, 2026 at 1:49 pm October 15, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Jun Li, Zhou Qiu, Xin Zheng, Runyu Xia, Hou Qian, Weifeng Li, Yufan Wu, Bo Pan, Xuemei Wang, Zhengzheng Huang, Dayong Gu, Yike Wu
LC–MS/MS quantification of trimethylamine N-oxide in plasma and volumetric absorptive microsamples: analytical validation and feasibility in pediatric kidney transplant recipientson October 14, 2026 at 1:26 pm October 14, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Paweł Czarnowski, Agnieszka Czajkowska, Jacek Rubik, Arkadiusz Kocur
Cardiac troponin autoantibodies and cancer therapy-related cardiac dysfunction in breast cancer patients receiving anthracycline treatment: secondary analysis of the PRADA studyon October 14, 2026 at 1:26 pm October 14, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Helea Junes, Victoria Vinje-Jakobsen, Siri L. Heck, Geeta Gulati, Torbjørn Omland, Saara Wittfooth
From promise to practice: Assessing middleware characteristics in autoimmune diagnosticson October 14, 2026 at 1:26 pm October 14, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Emirena Garrafa, Brunetta Porcelli, Valentina Muraro, Rocco Negri, Barbara Casolari, Maria Infantino, Giampaola Pesce, Nicola Bizzaro
Study of biallelic variants in CYP2R1 causing vitamin D hydroxylation deficiency rickets type 1Bon October 10, 2026 at 10:42 am October 10, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Jiasheng Zhang, Yuhui Huang, Juan Li, Wan Huai, Xin Li, Yanrong Qing, Ruen Yao, Xiumin Wang, Tingting Yu, Fuxiang Chen
RefInterval studio: development of a guided R shiny workflow for establishing discrete and age-continuous reference intervalson October 10, 2026 at 10:42 am October 10, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Ma Chaochao, Zhou Haoyi, Cheng Xinqi, Chen Shi, Pang Haiyu, Xu Tengda, Wang Danchen, Hou Lian, Qiu Ling
Soluble suppression of tumorigenicity 2 and cardiovascular outcomes across serum uric acid strata in maintenance hemodialysis: an exploratory secondary analysison October 9, 2026 at 9:48 am October 9, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Yiqi Su, Zhen Zhang, Liyu Lin, Jie Teng, Xiaoqiang Ding, Jianzhou Zou
Impact of ISO/TS 20914-based measurement uncertainty on HbA1c classification around clinical decision limits: A real-world evaluation of two analytical systemson October 9, 2026 at 9:48 am October 9, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Ahmet Burak Gürpınar, Canan Karadağ, Muzaffer Katar
Performance assessment of a novel fully automated ELISA for anti-IA2 autoantibody detection in type 1 diabeteson October 8, 2026 at 9:07 am October 8, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Martina Lehmann, Gia-Gia Toni Hò, Petra Augstein, Malgorzata Baranowska-Dell, Cornelia Dähnrich, Andrea Deerberg, Sandra Saschenbrecker, Wolfgang Kerner, Lars Komorowski, Alexander Kühnl, Kai Masur, Christian Probst, Sina Rhein, Michael Schlosser, Skander Elleuche
A rapid sequential salting-out/isoelectric precipitation LC-MS/MS method for quantifying cytokeratin 18 in human ascitic fluidon October 8, 2026 at 9:07 am October 8, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Zhenni Liu, Xiaohua Xiao, Bingchu Li, Nijiao Qin, Ziyang Li, Xing Lyu, Zhongyuan Xiang, Min Hu, Qichen Long
Comparative diagnostic utility of cerebrospinal fluid biomarkers in multiple sclerosison October 7, 2026 at 2:33 pm October 7, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Basant Rashad, Sohair K. Sayed, Tarek A. Rageh, Eman R. Badawy, Dalia T. Kamal
A novel γ-chain Tyr306Asn missense mutation causes congenital dysfibrinogenemiaon October 6, 2026 at 2:02 pm October 6, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Yangyang Wu, Lu He, Chen Qian, Meiling Luo, Qinghui Luo, Liqun Xiang, Min Chen, Xinyan Chen, Lin Liao, Jie Yan, Faquan Lin
Adjustment and validation of convolutional neural network for indirect immunofluorescence interpretation of antinuclear and anti-neutrophil cytoplasmic antibodies: A multicenter studyon October 2, 2026 at 12:04 pm October 2, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Rulin Jia, Yun Li, Jing Hu, Xianzi Cong, Yinxue Ma, Jianping Guo, Zhiyan Li, Haiping Zhang
Three FBN1 pathogenic variants in Chinese patients with Marfan syndrome: Two novel variants including a splicing-altering deletion with functional verificationon October 2, 2026 at 12:04 pm October 2, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Xing Zhao, Lamei Yuan, Yan Sun, Hong Xia, Pengzhi Hu, Hongbo Xu, Lina Gong, Hao Deng
Three failure modes, three remedies: a creatinine-triggered reflex for pediatric urine drug screeningon October 1, 2026 at 11:15 am October 1, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Nezihe Köker Özer, Ercan Yılmaz, Didem Tatar
Machine learning-based discrimination of metabolic dysfunction-associated steatotic liver disease: implications of tryptophan metabolites as potential biomarkerson September 29, 2026 at 3:56 pm September 29, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Zhenni Liu, Siying Li, Yaxin Tan, Bingchu Li, Nijiao Qin, Peiting Liu, Fengfan Li, Zhiyang Chen, Ziyang Li, Xing Lyu, Xiangyu Zhang, Zhongyuan Xiang, Min Hu, Qichen Long
A clinical decision support framework for automated M-protein isotype classification from capillary zone electrophoresis immunotyping signalson September 27, 2026 at 1:26 pm September 27, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Deniz İlhan Topcu, Nilüfer Bayraktar, Erdinç Devrim
Detection profiles of multiplex real-time PCR and culture for Streptococcus pneumoniae in pediatric lower respiratory tract infectionson September 25, 2026 at 11:41 am September 25, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Jing Guo, Weiyuan Zhuo, Chenglan Yan, Jialing Ruan, Linlin Li
Clinical utility of the lipemic index for identifying severe triglyceride-rich lipoprotein disorders in adults undergoing routine blood testingon September 24, 2026 at 5:15 pm September 24, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Pauline C.E. Schuitema, Hans Kemperman, Simone Smits, Cornelis A. Koekman, Wouter W. van Solinge, Raymond M. Schiffelers, A. David Marais, Frank L.J. Visseren, Charlotte Koopal
Biofluid iodine concentrations are associated with mild cognitive impairment: The potential mediating role of thyroid hormoneson September 24, 2026 at 5:15 pm September 24, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Zijian Jin, Pengxin Li, Yu Zhu, Meina Ji, Mingli Zheng, Xiwen Fu, Qi Jin, Ziyun Pan, Elizabeth N. Pearce, Wenxing Guo, Wanqi Zhang
Ionized magnesium in serum measured using a blood gas analyser: Agreement with whole blood, short-term stability and preliminary reference interval in healthy adultson September 24, 2026 at 5:15 pm September 24, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Carlos Castillo Pérez, Purificación Jurado Parras, Raquel Ramos Corral
Assay-dependent reclassification of biochemical hyperandrogenism in female androgen testing: CLIA versus LC-MS/MS under common clinical decision thresholdson September 23, 2026 at 10:30 am September 23, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Xianhua Zhang, Huiyu Xu, Lingling Liu, Li Yang, Rong Li, Rongsheng Zhao
Metabolic and liver enzyme correlates of serum alpha-fetoprotein in a large health check-up populationon September 22, 2026 at 9:56 am September 22, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Lu Zhou, Huan Wu, Tao Wu, Xinru Wang, Errui Song, Fan Su, Catherine Adaeze Ezeokafor, Yue Wu, Xinyu Ma, Tong Wang, Yufeng Wen
Hematological and biochemical profiling of iron deficiency anemia among adolescent girls: A cross-sectional study from rural areas of the Jungle Mahal, West Bengal, Indiaon September 22, 2026 at 9:56 am September 22, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Sumita Rani Pradhan, Kartik Chandra Guchhait, Suparna Majumder, Debarati Jana, Biswajit Das, Mousumi Manna, Pradip Jana, Amiya Kumar Panda, Chandradipa Ghosh
Diagnostic and prognostic performance of heart-type fatty acid–binding protein in functionally relevant coronary artery diseaseon September 21, 2026 at 9:26 am September 21, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Evangelos Tsianakas, Seval Kul, Fiona Nafaa, Koray Durak, Pedro Lopez-Ayala, Emel Kaplan, Gabrielle Huré, Alex Ritz, Luca Koechlin, Ivo Strebel, Philip Haaf, Simon Frey, Felix Mahfoud, Michael T. Zellweger, Christian Mueller
Medium-chain acyl-CoA dehydrogenase deficiency: A ten-year single-center case series from Indiaon September 19, 2026 at 2:21 pm September 19, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Radha Rama Devi Akella, Srilatha Kadali, Shaik Mohammad Naushad
Continuous versus discrete reference intervals for pediatric thyroid hormones: Clinical implications from a GAMLSS-based reclassification analysison September 18, 2026 at 1:35 pm September 18, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Merve Türkegün Şengül, Didem Derici, Saniye Başak Oktay
Association of perfluoroalkyl and polyfluoroalkyl substances with polyendocrine metabolic ovarian syndrome and endocrine abnormalities: A case–control studyon September 17, 2026 at 12:50 pm September 17, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Guan Cheng, Fangning Li, Hongyu Li, Youran Li, Yan Cao, Ying Liu, Dan Huang, Wenxiang Liu, Mingwei Xin, Hongjian Miao, Yanhong Zhai, Zheng Cao
Rapid myocardial infarction rule-out: A single high-sensitivity cardiac troponin I and T threshold strategy for the Chinese emergency departmenton September 15, 2026 at 5:32 pm September 15, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Yang Fangfang, LinYahui, Zhan Hong, Wang Shukui, Liu Min, Ye Zi, Liu Caidong, Feng Guangxun, Zhang Tao, Zhu Jun, Fu Yenan, Liang Yan, Zhou Zhou
Site-specific glycosylation of serum antithrombin-III as a potential biomarker for AFP-negative HCCon September 13, 2026 at 10:25 am September 13, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Xinyi Cao, Zhao Cao, Huan Zeng, Yao Hu, Cuiping Zhang, Guoquan Yan, Lei Zhang, Hong Shu, Haojie Lu, Ming Guan
Enzyme-free voltammetric sensor for monitoring of creatinine in diabetic patient using sustainable L-cysteine/AuNPs/rGO nanocompositeon September 12, 2026 at 3:40 pm September 12, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Mayuri M. Ghatage, Vishakha S. Parkhe, Sohel B. Shaikh, Tukaram D. Dongale, Arpita Pandey-Tiwari
Comparative performance of age-continuous and conventional reference intervals in long-term validation: A 10-year health examination cohort study of serum creatinineon September 10, 2026 at 3:02 pm September 10, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Shuling Chi, Chaochao Ma, Xiaoqi Li, Xuehui Gao, Lian Hou, Xiuzhi Guo, Yunyun Fei, Ling Qiu
Evaluation of the predictive value of sCD200 and sCD200R for disease severity and relapse in myasthenia gravison September 8, 2026 at 12:08 pm September 8, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Yajie Chen, Jinjing Jia, Yang Xu, Yunfei Zhu, Yanzheng Gu, Jingluan Tian, Qun Xue
Correlations between cerebrospinal fluid and plasma levels of GABA, glutamate, dopamine, and related metabolites, and their concentrations across neurological disorderson September 8, 2026 at 12:08 pm September 8, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Yuhang Deng, Wenqing Wu, Sumei Han, Haoqin Jiang, Ming Guan
Translational optical and electrochemical biosensing strategies for liquid biopsy in triple-negative breast Cancer: advances, challenges, and clinical implementationon September 8, 2026 at 12:08 pm September 8, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Karim G. Mohammed, Mohamed Essameldin Abdelgawad, Mohamed S. Attia
Pooling samples for a high-sensitivity cardiac troponin validation may miss an acute phase response interferenceon September 6, 2026 at 10:52 am September 6, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Peter A. Kavsak
Targeted amino acid profiling reveals early metabolic alterations in young-onset type 2 diabetes mellituson September 5, 2026 at 4:09 pm September 5, 2026 Publication date: 15 March 2027 Source: Clinica Chimica Acta, Volume 594 Author(s): Bhanu Prasad Palivela, Vijayasarathy Ketavarapu, Divya Presingu, Keerthi Reddy, Ramunaidu Addipilli, Mitnala Sasikala, Jagadeshwar Reddy Thota
Spurious undetectable albumin due to hemodialysis catheter lock contaminationon August 30, 2026 at 9:37 am August 30, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Ahmet Namlı, Hasan Alp Turgut, Mehmet Şeneş
A 4-year-old male presenting with frequent falls, clumsily rising from seated positions, but a normal creatine kinaseon August 15, 2026 at 12:02 pm August 15, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Jude Abadie
Effect of the unreported COL5A2 variant c.2499 + 4_2499 + 5insTAA on RNA splicing: Insights from minigene assayson August 15, 2026 at 12:02 pm August 15, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Zhongying Zhao, Lianrui Tang, Jing Zhu, Bingbo Zhou, Xinyuan Tian, Yupei Wang, Furong Liu, Hairui Pan, Ling Hui, Chuan Zhang
Analytically accurate, clinically inaccurate: A diagnostic case of Pseudohyperparathyroidismon August 13, 2026 at 4:15 pm August 13, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Chelsea B. Swartchick, Jodi L. Boysen, Ryan W. Pearce, Nikola A. Baumann, Brooke M. Katzman
Procalcitonin measurement uncertainty around Sepsis-related decision thresholds: Monte Carlo modeling from a large-scale clinical laboratory dataseton August 13, 2026 at 4:15 pm August 13, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Beyza Haytaç, Gamze Gök, Özcan Erel, Ceylan Bal
Clinical chemistry reference intervals in clinically validated healthy individuals: A large single-center studyon August 11, 2026 at 2:02 pm August 11, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Rob F.M. Oude Elferink, Shirly A.M. Wübbels, Geert Sloots, Anja Koster, Jan Leendert P. Brouwer
Integrated DIA proteomics of tissue and exudate reveals screening markers for early detection of ulcerative colitis and colorectal canceron August 11, 2026 at 2:02 pm August 11, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Qian Gong, Jin Wang, Qing Ke, Shuangshuang Du, Sinian Huang, Ting Zhu, Hao Qu, Ran Xu, Jiandong Zhang, Bin Yan, Jinjin Wang
An accessible digital single-molecule sensing platform for plasma P-tau217 quantification in Alzheimer’s disease screeningon August 7, 2026 at 9:57 am August 7, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Meng Xue, Hongchao Pan, Yana He, Haiyan Li, Hailan Zhou, Keding Cheng, ChuangChuang Xiao, Jie Zhao, Xiaodong Jia, Yan Li, Dequan Liu, Keqiang Yan
The utilization of multiplex PCR with fragment analysis for carrier screening of spinal muscular atrophyon August 6, 2026 at 3:01 pm August 6, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Kunvara Orachon, Watcharapa Jaranasaksakul, Preyaporn Onsod, Teerapong Siriboonpiputtana, Budsaba Rerkamnuaychoke, Takol Chareonsirisuthigul
From analytical bias to threshold-based discordance: An ID-LC-MS/MS reference method reveals and corrects hyperhomocysteinemia classification discordance in Chinaon August 6, 2026 at 3:01 pm August 6, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Kaiduo Xu, Yunmiao Sun, Xuanchang Bai, Jing Wang, Jiangtao Zhang, Haijian Zhao, Weiyan Zhou, Chuanbao Zhang
Diagnostic performance and interference analysis of a chemiluminescent H. pylori stool antigen assay stratified by 13C-urea breath test values in a multicenter studyon August 5, 2026 at 1:37 pm August 5, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Zixia Wang, Xiaozhong Chen, Huiqiong Lu, Qianyun Deng, Liuqin Chen, Yue Meng, Beibei Wang, Lei Wang, Wei Fang
Transferrin-derived TIBC, a flagged but normal resulton August 5, 2026 at 1:37 pm August 5, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Martin Safran, James Corines, Matthew Elkins, Michel R. Nasr, Katalin Banki, Zhimin Tim Cao
Microwave-assisted hydrolysis and HPAEC-PAD for simultaneous quantification of sialic acid and six other glycan monosaccharides in human serum: RSM optimization, validation, and proof-of-concept application to acute strokeon August 2, 2026 at 5:00 pm August 2, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Meng Zhang, Lijuan Zhang, Hong Lu, Yiran Zhang
Bis(monoacylglycero)phosphate (BMP) as a circulating biomarker of lysosomal dysfunction in GNE myopathyon August 1, 2026 at 10:17 am August 1, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Cristina Manis, Fabrizio Pertusati, James Morewood, Andreas Roos, Felix Kleefeld, Michela Onali, Oksana Pogoryelova, Alexa Derksen, Sally Spendiff, Hanns Lochmuller, Paula Videira, Luigi Atzori, Pierluigi Caboni
Application-related patterns of diluted urine specimens in routine urine drug testing: A retrospective specimen-record-level studyon August 1, 2026 at 10:17 am August 1, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Mehmet Akif Bozdayi, Gökhan Çakırca, İsmet Gamze Bozdayi
Diagnostic pitfall: NSAID-induced membranous nephropathy with PLA2R positivity, IgG1-predominant deposits, C1q positivity, and concurrent acute interstitial nephritis—A case reporton July 30, 2026 at 2:48 pm July 30, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Jingzhen Li, Qianqian Zhang, Zhengyue Chen, Yingyin Qiu, Yuanping Liu
Advanced algorithm for correcting cold agglutination interference in red blood cell parameters with the Mindray BC-7600 hematology analyzeron July 30, 2026 at 2:48 pm July 30, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Bo Ye, Jiong Zhang, Wenbo Zheng, Danzhou Tao, Zhongfu Zhang, Yushuai Ma, Taiqiang Zhao
Development of a liquid chromatography coupled to tandem mass spectrometry method for the quantification of Arginine Vasopressin in human plasmaon July 30, 2026 at 2:48 pm July 30, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): E. Grifnée, E. Cavalier, C. Le Goff
Automated detection of intravenous fluid contamination using longitudinal routine laboratory data: development and external validation of a multitask learning frameworkon July 29, 2026 at 2:06 pm July 29, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Jordi Tortosa-Carreres, Nahúm Martí-Montoro, Jonnathan Andrés Acevedo-Galvis, Cristel Pascual-Escrivà, Ricardo Alonso-Díaz, Óscar Fuster-Lluch, Laura Sahuquillo-Frias, Begoña Laiz-Marro
Specific serum metabolites can differentiate severe and mild human traumatic brain injuryon July 29, 2026 at 2:06 pm July 29, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Lei Shi, Zhuonan Wang, Jie Zhang, Ping Zheng, Lijun Bai
Reduced fecal GP2 levels in ulcerative colitis associate with inflammatory activity and microbial compositionon July 29, 2026 at 2:06 pm July 29, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Yoav Uchitel, Dirk Roggenbuck, Haim Leibovitzh, Nathaniel Aviv Cohen, Rony Izhar, Lior Lobel, Nitsan Maharshak, Lael Werner
An ID-HPLC-MS/MS based candidate reference measurement procedure for the quantification of ceramides in human serumon July 26, 2026 at 11:38 am July 26, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Huoyan Ji, Xiaozhen Zhang, Xiaofan Yin, Xiaodong Yang, Weiming He, Min Shen
Multiplex methylation marker analysis for ctDNA detection in liquid biopsies from anal cancer patients: an HPV-independent approachon July 25, 2026 at 10:42 am July 25, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Søren Kahns, Luisa M.D. Canto, Laura E. Stokkebro, Jonna S. Madsen, Renske D.M. Steenbergen, Jan Lindebjerg, Claus Varnum, Birgitte M. Havelund, Lars H. Jensen, Torben F. Hansen, Anders K.M. Jakobsen, Karen-Lise G. Spindler, Rikke F. Andersen
Pheochromocytoma as a manifestation of Neurofibromatosis type 1: Clinical presentation, diagnosis, and genetic analysison July 25, 2026 at 10:42 am July 25, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Neus Baena-Díez, Ruth Cano-Corres, Elisabet Castellanos, Josep Leon Mengibar, Ismael Capel Flores
Hyperuricemia, circulating metabolites, and the risk of cardiometabolic multimorbidityon July 24, 2026 at 3:42 pm July 24, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Ziyi Zhou, Yin Wu, Yuan Fei, Jiaheng Chu, Shuo Jiang, Weisheng Xu, Xiaoqi Zheng, Hui Wang
Association of the triglyceride-glucose index with tumor burden in newly diagnosed multiple myeloma: A retrospective cross-sectional studyon July 24, 2026 at 3:42 pm July 24, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Jing Zhang, Dan Xu, Ran Luo, Wentao Shu, Dongfeng Zeng, Xiaona Bu
Urine culture contamination in a tertiary hospital: Demographic predictors and direct economic impacton July 22, 2026 at 2:21 pm July 22, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Marcos Palma-Lopez, Luis Roberto Galindo-Mendez
A novel urinary metabolic signature for the non-invasive screening of lupus nephritis in systemic lupus erythematosuson July 20, 2026 at 12:02 pm July 20, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Zhifang Yao, Ping Yang, Xiang Qian
Investigating non-reproducible high-sensitivity cardiac troponin T results in real-world practiceon July 19, 2026 at 11:30 am July 19, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Zeynep Şule Evren, Kamil Taha Uçar
Plasma nerve growth factor level is associated with functional outcome after ischemic strokeon July 17, 2026 at 9:31 am July 17, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Yiming Jia, Lulu Sun, Mengyao Shi, Daoxia Guo, Yanbo Peng, Tan Xu, Yonghong Zhang, Zhengbao Zhu
Establishment and validation of intelligent review rules for blood cell analysis based on the gradient boosting decision tree algorithmon July 16, 2026 at 2:40 pm July 16, 2026 Publication date: 15 February 2027 Source: Clinica Chimica Acta, Volume 593 Author(s): Wenjia Tang, Shaoqian Chen, Zhenglin Yu, Xiumei Gu, Baishen Pan, Beili Wang, Rong Ding, Shihong Zhang, Chong Wang, Jing Lin, Wei Guo
Integrating lung microbiome, amino acid metabolism, and host immune response in elderly patients for severe lower respiratory Infections diagnosis: a multi-omics studyon July 16, 2026 at 2:40 pm July 16, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Tianqi Qi, Qian Liu, Manyu Li, Haoyang Li, Guowei Liang, Wenjun Tu
Chemometric profiling reveals selective circulating bile acid remodeling in Alzheimer’s diseaseon July 14, 2026 at 12:03 pm July 14, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): M. Emam, Fatema S. Alatawi, Yasser Alzamil, Nisreen Haj, Amani A. Mahbub, Amna Mohamed Ahmed, Sara Albadri, Malik Bader Alazzam, For the Alzheimer’s Disease Neuroimaging Initiative
Development and validation of patient-based exponentially weighted moving average quality control models for three antipsychotic drugs and their metabolites by LC-MS/MSon July 13, 2026 at 11:21 am July 13, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Qi Guo, Yungang Pu, Jing He, Sihai Ling, Canjun Ruan, Guixin Guo, Chunyan Zhou, Chengeng Liu, Xiangyi Liu
NT-IGFBP-4: A novel biomarker for risk prediction in acute heart failureon July 12, 2026 at 10:52 am July 12, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Ling Li, Jing Wang, Chen Chen, Yu Wu, Juan Yang, Xin Shu, Litao Zhang, Yi Zhang, Zhenlu Zhang
Development and commutability assessment of serum-based candidate reference materials for homocysteine and their application in external quality assessmenton July 11, 2026 at 4:29 pm July 11, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Wenxuan Fu, Lijuan Zhang, Jie Shi, Mo Wang, Shunli Zhang, Rui Zhang
Personalized reference intervals for biochemical, hormonal, and coagulation tests: Comparison with population-based reference intervalson July 11, 2026 at 4:29 pm July 11, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Musab Kazar, Murat Aksit, Ayfer Colak, Deniz İlhan Topcu
Serum sialic acid is independently associated with cerebrovascular atherosclerotic stenosis severity and total vascular burden: A retrospective cohort studyon July 10, 2026 at 9:56 am July 10, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Qi Cai, Chunjiao Yang, Lei Luo, Yinfei Huang, Yu Xie, Xin Liang, Renwei Zhang, Yumin Liu
Serum IgG, definite anti-dsDNA positivity, and advanced HBV-related liver disease: a laboratory-based retrospective studyon July 10, 2026 at 9:56 am July 10, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Hui Chen, Xue Han, Chen Qian, Shuo Jiang, Guojun Zheng, Zhou Zhang
A follow-up cohort study on secondary findings in cancer predisposition genes from 20,205 Chinese individualson July 10, 2026 at 9:56 am July 10, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Jiaqi Xu, Jin Sun, Jie Tang, Wan Huai, Yijin Gao, Ruen Yao, Tingting Yu
Glycated albumin beyond HbA1c: an equity-ready laboratory pathway for emergency diabetes and cardiorenal risk screeningon July 8, 2026 at 9:20 pm July 8, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Anurag Prasad, Rajesh Prasad Jayaswal
Letter to the editor regarding: “Glycosylation-associated plasma SNORD99 as a novel diagnostic biomarker for early-stage lung adenocarcinoma”. Clinica Chimica acta 580(2026) 120722on July 8, 2026 at 9:20 pm July 8, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Pei Gao, Fu Liu, Meiyuan Liu, Juan Yu
Reference intervals for venous blood gas measurement in a healthy Chinese populationon July 8, 2026 at 9:20 pm July 8, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Sheng Jiang, Qian Zhao, Hua Wang, Min Li, Yuanzhu Ou, Weiwei Lin
Performance of Free Light Chain reagents in the Dutch External Quality Assessment programme over the past 14 yearson July 8, 2026 at 9:20 pm July 8, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Moniek M. Bioch, Corrie M. de Kat Angelino, Anke J. ten Haaken-Meijer, Marc H.M. Thelen, Joannes F.M. Jacobs
Comparing conventional correction formulas and machine learning-based prediction of ionized calciumon July 8, 2026 at 9:20 pm July 8, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Arzu Kösem, Ali Öter, Şeref Sağıroğlu, Sevilay Sezer, Canan Topçuoğlu, Gülsen Yılmaz
M-protein detection using two immunofixation electrophoresis systems and impact of daratumumab interference on disease monitoringon June 25, 2026 at 12:26 am June 25, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Saki Kushima, Tomofumi Nakamura, Rika Fukushima, Ayako Ishihara, Yawara Kawano, Daisuke Mori, Yasuhito Tanaka
Evaluating circulating tumor DNA methylation patterns of a multi-gene panel for colorectal cancer diagnosis: A pilot studyon June 25, 2026 at 12:26 am June 25, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Faten Usrof, Karima M. Abu Helal, Mohammed J. Ashour, Hadeer N. Abuwarda, Mazen M. Alzaharna, Fadel A. Sharif
Xpert® bladder Cancer monitor urine test for non-muscle-invasive bladder cancer surveillance: a prospective clinical trialon June 25, 2026 at 12:26 am June 25, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Mohamed Trabelssi, Pierre-Jean Lamy, Jean-Pierre Daures, Françoise Perriard, Grégoire Poinas
A survey of external quality assessment schemes (EQAS) for faecal immunochemical tests for haemoglobin (FIT)on June 25, 2026 at 12:26 am June 25, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Carolyn Piggott, Marc Thelen, Sam Jones, Petr Kocna, Marieke Frasa, Eline A.E. van der Hagen, Sally C. Benton, on behalf of the International Federation of Clinical Chemistry Faecal Immunochemical Test Working Group (IFCC FIT-WG)
Irisin as a multi-target renoprotective mediator in chronic kidney disease: from molecular mechanisms to therapeutic perspectiveson June 25, 2026 at 12:26 am June 25, 2026 Publication date: 1 January 2027 Source: Clinica Chimica Acta, Volume 592 Author(s): Shubhdeep Singh Bandral, Sapna Ahuja, Thakur Gurjeet Singh, Rupinder Kaur
Diagnostic accuracy of NGAL and HBP for the diagnosis of acute bacterial meningitison May 22, 2026 at 8:13 am May 22, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Haoqin Jiang, Di Wang, Qitong Zhang, Wenqing Wu, Ning Li, Yuting Wang, Qianqian Xu, Liu Dong, Shirong Li, Ming Guan
Laboratory testing for anti-synthetase antibodies: a novel algorithm to improve diagnostic accuracyon May 22, 2026 at 8:13 am May 22, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Andrés Baucells, Laura Martínez-Martínez, Mireia Fonolleda, Maria Rosa Julià, Juliana Ochoa Grullón, Cándido Juárez, Eduard Gallardo, Anaís Mariscal
Holotranscobalamin-based algorithm for the identification of macro-vitamin B12 in analytical hypercobalaminemiaon May 22, 2026 at 8:13 am May 22, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Patricia Fernández-Tomás, Leyre Ruiz, Estíbaliz Alegre, Álvaro González
