A New CRC Blood Test Is Here. What Does It Mean for Screening?

In July, the US Food and Drug Administration (FDA) approved a new blood-based test to screen for colorectal cancer (CRC). The FDA’s approval of Shield (Guardant Health) marks a notable achievement, as individuals at average risk now have the option to receive a simple blood test for CRC screening, starting at age 45. “No one has an … Read more

Master copper regulator discovery may offer Alzheimer’s clues

New therapeutic opportunities often emerge from research on simple organisms. For instance, the 2020 Nobel Prize in Chemistry awarded to Emmanuelle Charpentier, Ph.D., and Jennifer Doudna, Ph.D., for their CRISPR-based DNA editing discovery began with studies using bacteria just a decade prior. Today, CRISPR therapies are approved for several disorders, and more such treatments are … Read more

Rapid blood diagnostic test developed for amyotrophic lateral sclerosis

A highly accurate diagnostic blood test has been developed for amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease that affects neurons in the brain and spinal cord. ALS leads to gradual paralysis, ultimately resulting in the inability to walk, speak, or, in later stages, move. Currently, diagnosis is based on a thorough clinical examination, but … Read more

What makes urine yellow? Scientists discover the enzyme responsible

Researchers at the University of Maryland and National Institutes of Health have identified the microbial enzyme responsible for giving urine its yellow hue, according to a new study published in the journal Nature Microbiology. The discovery of this enzyme, called bilirubin reductase, paves the way for further research into the gut microbiome’s role in ailments like jaundice … Read more

Researchers identify circulating proteins linked to preeclampsia and other hypertensive disorders of pregnancy

Preeclampsia and other hypertensive disorders of pregnancy—which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy—carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited. A team led by researchers at Massachusetts General Hospital (MGH) and the … Read more

New tumor marker can detect gastric cancer with nearly 90% accuracy

New tumor marker can detect gastric cancer with nearly 90% accuracy (medicalxpress.com) A research team led by the Nagoya University Graduate School of Medicine has discovered that the stromal cell-derived factor 4 (SDF-4) protein is a reliable cancer marker. As simple blood tests accurately detect the protein, their findings suggest the potential of the marker … Read more

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