Inflammatory-nutritional biomarker scores and risk of malignant effusion in a pan-cancer cohort of 68,916 patients: Nonlinear associations and machine learning validationon April 1, 2026 at 8:04 pm April 1, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): R.N. Haoyu Liu, R.N. Yunhui Chen, R.N. Shouyan Wang
Determination of age-specific reference intervals for ethanolamine plasmalogen species in red blood cells using liquid chromatography tandem mass spectrometryon April 1, 2026 at 12:47 am April 1, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Irene De Biase, Malgorzata Miller, Lauren M. Zuromski, Katherine J. Anderson, Stacey L. Cole, Preejith P. Vachali, Tatiana Yuzyuk
High-throughput quantification of tacrolimus in whole blood by acoustic ejection mass spectrometry: analytical validation and comparative assessment against conventional LC-MS/MS for therapeutic drug monitoringon March 31, 2026 at 6:16 am March 31, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Xin-Yu Wu, Xiao-Kang Fu, Ao Li, Wei Zhang, Han-Peng Jiang, Na An, Quan-Fei Zhu, Shao-Ting Wang, Yu-Qi Feng
Thyroid hormone profile and biological variation in a population of athletes during an entire sport seasonon March 31, 2026 at 6:16 am March 31, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Isabel Moreno-Parro, Jorge Díaz-Garzón, Berta Sufrate-Vergara, Aasne K. Aarsand, Sverre Sandberg, Anna Carobene, Outi Itkonen, William Bartlett, Abdurrahman Coskun, Niels Jonker, Pilar Fernández-Calle, on behalf of theEuropean Federation of Clinical Chemistry and Biological Variation Committee
Stability of serum metabolites following delayed centrifugationon March 31, 2026 at 6:16 am March 31, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Antonio Minò, Cristiana Tiberio, Marika Caruso, Alfonso Di Costanzo, Antonella Angiolillo
Intraoperative tissue aspirate testing: A single-center experience and evaluation of criteria for parathyroid tissue confirmationon March 29, 2026 at 11:13 am March 29, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Jillian Kodger, Natalie Merchant, Joe M. El-Khoury, Jennifer B. Ogilvie, Adriana G. Ramirez, Thomas J.S. Durant
Metabolic and mitochondrial alterations in children with autism spectrum disorder: The role of FGF-21 and GDF-15on March 29, 2026 at 11:13 am March 29, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Ayla Yildiz, Hanim Seyma Topuz, Hasan Onal
A laboratory puzzle in a “blue” adolescent: Cyanosis, discordant oxygen measurements, and interference in leukocyte differential analysison March 25, 2026 at 11:50 am March 25, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Lianhui Yu, Zhongjie Yang, Liyuan Dai, Clarence W. Chan, Xuzhen Qin
Genetic determinants of aggression in schizophrenia: The role of MAOA rs1465108 and BDNF rs6265 polymorphismson March 25, 2026 at 11:50 am March 25, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Sariye Aybüke Yıldırım, Irmak Dal, Selin Özkan-Kotiloğlu, Fatih Özdemir, Osman Topçu, Burçin Çolak, Bora Baskak, Dilek Kaya-Akyüzlü
Profiling plasma transthyretin in healthy subjects and patients with cardiac ATTR amyloidosis by native electrophoresison March 25, 2026 at 11:50 am March 25, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Maria Franzini, Chiara Sanguinetti, Veronica Musetti, Francesco Greco, Lidia Ciccone, Susanna Nencetti, Silvia Masotti, Vanessa Susini, Vincenzo Castiglione, Alberto Aimo, Liam A. McDonnell, Giuseppe Vergaro, Michele Emdin
Meropenem interference on phosphate measurement: utility of reaction curve analysis in automated biochemistry analyzerson March 21, 2026 at 1:47 pm March 21, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Chun-Fung So, Rachel Sze-Wan Yiu, Tsz-Ki Ling, Man-Ting Wong, Melody Yee-Man Wong, Felix Chi-Kin Wong, Timothy Ming-Him Yeung, Ching-Wan Lam
The label-free electrochemical S100B-TBI immunosensor for sensitive detection of S100B protein as a biomarker for traumatic brain injury using FFT-SWV voltammetryon March 19, 2026 at 1:36 pm March 19, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Mehrasa Rahimi Borumand, Mojtaba Mojtahedzadeh, Shokoufeh Hassani, Mazda Rad-Malekshahi, Hashem Kazemzadeh-Beneh, Parisa Kianpour, Fatemeh Babaloii, Marziye Karimzade, Amirmahdi Mojtahedzadeh, Parviz Norouzi, Hamid Akbari Javar
Biological variation outweighs pre-analytical factors in coagulation reference intervals: a multicenter big data studyon March 19, 2026 at 1:36 pm March 19, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Fabio Del Ben, Gabriella Azzarini, Alessandra Brocca, Paola Centa, Maria Rita Cozzi, Claudio De Seta, Arianna Fassina, Elisabetta Fontanini, Roberta Giacomello, Giovanni Poli, Paola Pradella, Liliana Santarossa, Lorena Zardo, Benedetto Morelli
Recommendations for establishing metrological traceability for in vitro diagnostic measurement procedures intended to be used for whole blood sampleson March 17, 2026 at 6:39 pm March 17, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Jesper V. Johansen, Cas Weykamp, Elizabeth Barczak, Kevin Horan, Sverre Sandberg, Liesbet Deprez, Vincent Delatour, Mauro Panteghini, Neil Greenberg, Jeffrey Budd, Finlay MacKenzie, W. Greg Miller, for the IFCC Working Group on Commutability in Metrological Traceability
Extracellular vesicles in cardiovascular disease: Biomarkers, therapeutic applications, and drug delivery strategieson March 17, 2026 at 6:39 pm March 17, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Qamar Abuhassan, Amirali Salajegheh, Faris Anad Muhammad, Ali Fawzi Al-Hussainy, Tushar B. Gajjar, Malathi Hanumanthayya, Sandeep Kumar Shukla, Rajashree Panigrahi, Neeraj Bainsal, Djamila Polatova, Hayder Naji Sameer, Rasim M. Salih, Mohaned Adil
Beyond cholesterol: targeting inflammatory biomarkers in cardiovascular diseaseon March 17, 2026 at 6:39 pm March 17, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Qamar Abuhassan, Tamara Nazar Saeed, Ali Fawzi Al-Hussainy, Jalpa R. Patel, K.V. Jamuna, Vandana Tripathi, Samir Sahoo, Neeraj Bainsal, Djamila Polatova, Hayder Naji Sameer, Rasim M. Salih, Mohaned Adil
Metabolomics biomarkers for acute respiratory distress syndrome: a systematic review and meta-analysison March 17, 2026 at 2:20 am March 17, 2026 Publication date: 1 June 2026 Source: Clinica Chimica Acta, Volume 588 Author(s): Yuhong He, Hongxuan Liu, Weixia Li, Yuanyuan Yu, Huishu Lin, Shuhao Shi, Mengwei Lu, Hui Luo, Xiaoxue Li, Liqiong Guo
AI in the Prediction of Hepatic Fibrosis Progression Using Non-Coding RNAson March 17, 2026 at 2:20 am March 17, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Dibakar Roy, Md Sadique Hussain, Yumna Khan, Dhara N. Patel, Aseel Smerat, Neeraj Bainsal, Sumel Ashique, Arun Kumar, Irfan Ali Khan, Ochilova Dilorom, Muyassar Allaberganova, Anorgul Ashirova
Population-specific reference intervals for 22 biochemical analytes: three indirect methods application in a multi-ethnic areaon March 14, 2026 at 11:46 pm March 14, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Shengxi Zhang, Hua Zhang, Yan Li, Ziqiao Lin, Yingying Sun, Zhenzhen Dai
A laboratory-driven clinical decision support system algorithm for personalized and automated cardiovascular risk stratification in primary care patients.on March 14, 2026 at 11:46 pm March 14, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Jordi Tortosa-Carreres, Mónica Piqueras, Carlos Cátedra, Ana Vañó-Bellver, Diana Domingo-Valero, Teresa Claramunt-Carbonell, Luís Martínez-Dolz, Begoña Laiz-Marro
From bench to bedside: translating the histone deacetylase inhibitors into prostate cancer therapieson March 14, 2026 at 11:46 pm March 14, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Sandra Moreira Rocha, Mafalda Baptista Brás, Bruno J. Pereira, Cláudio J. Maia
Underutilization of fentanyl testing masks substantial fentanyl exposure in routine urine drug screens in Indianaon March 14, 2026 at 11:46 pm March 14, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Halimat Olaniyan, Jennifer Beckman, Elizabeth Crosby, David Shepherd, Samir Dahal, Dina Greene, Michelle K. Zimmerman, Rejwi A. Dahal
Exploring clinical feasibility of zero-shot learning in a large language model for immunofixation electrophoresis image interpretationon March 14, 2026 at 11:46 pm March 14, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Berrin Oztas, Irfan Kosesoy
Targeted next-generation sequencing in diagnosing reproductive tract infections: a comparative studyon March 14, 2026 at 11:46 pm March 14, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Zhiyang Chen, Ziyang Li, Li Tan, Xiaorui Yuan, Yan Yu, Hu Ge, Senmiao Zhang, Xiaomeng Xia, Min Hu
Resolving a complex GPIHBP1 exons 3–4 deletion adjacent to low-complexity repeats using adaptive sampling long-read sequencing in familial chylomicronaemiaon March 14, 2026 at 11:46 pm March 14, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Nike Kwai Cheung Lau, Hoi Shan Leung, Tammy Tsz Yan Tong, Yeow Kuan Chong, Chor Kwan Ching
CRISPR-Cas12a/Cas13a in cancer molecular diagnosison March 12, 2026 at 4:52 pm March 12, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Juncheng Lin, Yuyuan Wang, Biyun Zeng, Zhibing Chen, Xiaocong Lin, Tao Zeng
Liquid crystal-based biosensors for clinical diagnosticson March 12, 2026 at 7:25 am March 12, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Qamar Abuhassan, Jamal I. Al-Nabulsi, Subbulakshmi Ganesan, Subhashree Ray, V. Ramesh Kumar, Vipasha Sharma, Ashish Singh Chauhan, Zafar Aminov
Multi-omics biomarker detection in Diethylnitrosamine (DENA) induced hepatocellular carcinomaon March 12, 2026 at 7:25 am March 12, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Obaid Afzal, Pavan Goud, Kavita Goyal, Ali Altharawi, Mubarak A. Alamri, Manal A. Alossaimi, Abdulmalik S.A. Altamimi, Surya Nath Pandey
Performance evaluation of automated magnetic beads extraction method for the measurement of 23 plasma steroids using dual liquid chromatography-tandem mass spectrometry (LC-MS/MS) methodon March 12, 2026 at 7:25 am March 12, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Han Chen, Gang Xu, Mei-juan Zhang, Fu-rong Ying, Hai-xia Huang, He-huan Liu, Jian-rong Yang
Clinical application progress and prospects of non-invasive preimplantation genetic testing (niPGT): A reviewon March 12, 2026 at 7:25 am March 12, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Shaozhe Yang, Rongxiang Li, Bo Xu, Yongyong Wu, Junfeng Li, Xiuhong Fu
Artificial intelligence algorithm optimization and application in patient-based real-time quality control (PBRTQC)on March 12, 2026 at 7:25 am March 12, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Bowen Su, Yanpeng Zhang, Xiaomin Shi
Genetic screening of EIF2B genes reveals mutation spectrum and predicted prevalence of vanishing white matter disease in Chinese populationon March 9, 2026 at 7:36 pm March 9, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Xiaoli Liu, Ruolan Guo, Zhan Qi, Yaodong Zhang, Xiaotun Ren, Wei Li, Xuyun Hu, Chanjuan Hao
Small extracellular vesicles as emerging biomarkers and therapeutic targets in neurodegenerative diseaseson March 9, 2026 at 7:36 pm March 9, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Askarova Zebo Zafarjonovna, Elmuratova Aysulu, Sanoeva Matlyuba, Hamroyev Rashid, Jurakulov Bakhrom Azamatovich, Ahmadjonov Ahmadjon, Amirullayeva Barno, Azimova Mayram Kurbanovna, Mahsudali Rohataliyev Mahmudali ugli, Iskandarova Shaxodat, Turakulov Rustam, Matrizaeva Gulnara Jumaniyazovna, Alisher Ishankulov
Harnessing exosomes for precision diagnostics and therapies in psychiatry disorderson March 9, 2026 at 7:36 pm March 9, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Shaxlo Musinovna Xamidova, Achilova Donokhon, Kurbanov Obid, Rakhimova Gulnoz, Tolibov Dilshod, Tillashaykhova Khosiyat, Yazdankulova Gulnigor, Omarova Aynash, Abzairov Takhir, Shamsutdinova Guzel, Zaripova Oysara, Jorayev Shohruh, Вaratova Мexriban
Harnessing the gut–heart axis for cardiovascular drug innovation: microbiome, metabolites, and personalized treatment strategieson March 9, 2026 at 7:36 pm March 9, 2026 Publication date: 15 May 2026 Source: Clinica Chimica Acta, Volume 587 Author(s): Qhelen Mayline Chandra, Davini Clister, Princella Halim, Aminah Dalimunthe, Muhammad Ichwan, Dina Keumala Sari, Chindy Umaya, Nahida Aktary, Amama Rani, Moon Nyeon Park, Bonglee Kim, Rony Abdi Syahputra
Heat-resistant cryoglobulin investigated through dynamic cryoaggregation assay and mass spectrometryon March 9, 2026 at 7:36 pm March 9, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Jing Jing Wang, Chiang Lu, Enny Soesilowati, Manxin Gao, Adrian Y.S. Lee
Performance evaluation of an automated mass spectrometry system for the measurement and isotyping of monoclonal immunoglobulinson March 9, 2026 at 7:36 pm March 9, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Jamie Ashby, Daniel McEntee, Dhananjay Sakrikar, Luke Ouverson, Rhiannon Stanton, Nia Marrott, Roshani R. Patel, Cristina Simion, Syreeta Allen, Manisha Bhutani, David M. Foureau, Kaleb B. McLendon, Andrew S. Neish, Habib El-Khoury, Irene M. Ghobrial, David Barnidge, Gabriella Lakos, Mark Perkins, Stephen Harding, …
Read more Validation of parathyroid hormone measurement in fine-needle aspiration biopsy washings according to the IFCC LEAP checkliston March 9, 2026 at 7:36 pm March 9, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Ewa Kozłowska, Witold Chudziński, Aleksandra Kumorek, Olga Ciepiela
Methodological rigour and transparency are required for genotyping methods in genetic association studieson March 3, 2026 at 12:15 pm March 3, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Aditya K. Panda
Explainable machine learning framework based on blood biomarkers and routine health information for assistive diagnosis and risk stratification of acute myocardial infarctionon February 28, 2026 at 2:53 pm February 28, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Xinglong Zhu, Ting Wang, Jidong Jiang, Minghui Zhang, Tao Liu, Xiaodong Zhang, Yiqing Wang
Multi-omics biomarkers in cadmium-related lung toxicity and carcinogenesison February 28, 2026 at 2:53 pm February 28, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Khalid Saad Alharbi
EGFR as a biomarker in colorectal Cancer: An electrochemical biosensing approachon February 28, 2026 at 2:53 pm February 28, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Mohammed Khaled Bin Break, Rahamat Unissa Syed, Weiam Hussein, Muhammad Nawaz, Randa Abdeen Hussein Abdalla, Nayla Ahmed Mohammed Aboshouk, Teng-Jin Khoo, Hemat A. Elariny, Afrah E. Mohammed, Sahar S. Alghamdi
Umbilical cord mesenchymal stem cell exosomes in breast cancer. False hope or a real solution?on February 27, 2026 at 1:42 pm February 27, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Dana Jammoul, Toros Torossian, Mohamed Issa, May Saab, Chaza Harmouch, Rami Mhanna, Kawthar K. Abla
Engineered Bacteria as living detectors of tumor DNA: A new diagnostic frontieron February 26, 2026 at 12:46 pm February 26, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Abdolmajid Ghasemian, Ali H. Al-Marzoqi, Zahraa A. Ali, Fatemeh Nouruzi, Abbas Abdollahi, Zahra Montaseri, Mojtaba Memariani, Elham Zarenezhad
Urinary free cortisol analyses: Enhancing their clinical performance in Cushing’s syndrome management by means of LC-MS/MSon February 26, 2026 at 12:46 pm February 26, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Ana Rubio, Santiago Tofé, Antonia Barceló
Detection of thyroid hormones T3 and T4 in urine and serum after levothyroxine administration: A pilot study relevant to doping analysison February 26, 2026 at 12:46 pm February 26, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): T. Colpaert, K. Van Uytfanghe, G. T’Sjoen, N. Van Haecke, W. Van Gansbeke, P. Van Renterghem, M. Olijhoek, O. de Hon, G. Coppieters, P. Van Eenoo, K. Deventer
Glycated albumin: detection methods and standardizationon February 26, 2026 at 12:46 pm February 26, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Rui Wu, Tianjiao Zhang, Chuanbao Zhang
Gelsolin as a diagnostic biomarker in non-small cell lung Canceron February 26, 2026 at 12:46 pm February 26, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Imran Kazmi, Shakilur Rahman, Saleh Al Ghamdi, Mohammed Al-Zharani, Tarique Hussain Ashraf, Muhammad Afzal, Fahd A. Nasr, Faisal Fahad Almutairi, Sami I. Alzarea
Establishment of trimester-specific reference intervals for hemostatic and hematologic indices and their associations with adverse pregnancy outcomeson February 25, 2026 at 11:32 am February 25, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Huimin Shi, Jiayi Chen, Junwei Liu, Qingxiu Li, Bin Sun, Danwei Zhang, Zhengqin Wu, Haiyan Gao, Wei Li, Wenjuan Liu, Qian Zhang, Yibing Zhu, Haibo Li
Exploration of the source of AQP4 antibody: Based on paired serum and cerebrospinal fluid samples from 98 patientson February 25, 2026 at 11:32 am February 25, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Tao Wu, Haiqiang Jin, Hongjun Hao, Yiming Zheng, Jing Guo, Nan Zhang, Ran Liu, Zhaoxia Wang, Feng Gao
Study on the reference intervals of six androgen “backdoor pathway” steroids in healthy Chinese adultson February 24, 2026 at 10:26 am February 24, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Yongqi Liu, Susu Cai, Shixin Sun, Yuxia Han, Xujing Kong, Jianfeng Zhou, Baorong Chen, Zenghe Li
AIM2 inflammasome and pyroptosis biomarkers in oncologyon February 24, 2026 at 10:26 am February 24, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Rajiv Dahiya, Abedalrahman Shqaidef, Soumya V. Menon, Vaibhav Rathore, Sanjay Singh, Manjari Mittal, Lakshmi Thangavelu, Nardev Singh, Arti Mihir Hajarnavis, Waleed Hassan Almalki
Smoking-dependent circulating non-coding biomarkers in lung canceron February 21, 2026 at 1:31 pm February 21, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Abdullah Farasani
Pathophysiologic mechanisms and molecular targets in preeclampsiaon February 21, 2026 at 1:31 pm February 21, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Jinxuan Ren, Mei Yang, Qing Zhu, Menghui Wang, Nanfang Li
Assessment of non-invasive fibrosis scoring systems in pediatric MASLD: A retrospective comparison across healthy, MASLD, and biopsy-staged groupson February 20, 2026 at 12:54 pm February 20, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Nazmin Bithi, Sidharth Panda, Michael D. Dowlin, Sridevi Devaraj
The 22q11.2 deletion syndrome: Genetic mechanisms, clinical manifestations, and therapeutic strategieson February 19, 2026 at 12:22 pm February 19, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Shaozhe Yang, Yuan Zhuang, Shuwen Xin, Yanqi He, Xiuhong Fu
CYFRA 21-1 as a circulating biomarker in non-small cell lung canceron February 19, 2026 at 12:22 pm February 19, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Neelam Singla, Kavita Goyal, Pawan Goud, Vaishali Goel, Avijit Mazumder, K.P. Hemalatha, Vijayakumar Sachidananda, Gaurav Gupta, Sachin Kumar Singh, Kamal Dua, Brian Gregory George Oliver
Artificial intelligence and machine learning applications in dialysis: Current applications, challenges, and future directionson February 19, 2026 at 12:22 pm February 19, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Aanuoluwapo Clement David-Olawade, Muyiwa Ademola Ogunbona, Olabanke Florence Olawuyi, Babajide David Makanjuola, John Oluwatosin Alabi, David B. Olawade
Circulating integrins as biomarkers for bone metastasis in prostate canceron February 18, 2026 at 11:16 am February 18, 2026 Publication date: 15 April 2026 Source: Clinica Chimica Acta, Volume 586 Author(s): Bandar Theyab Alenezi, Abdullah R. Alzahrani, Zia Ur Rehman, Shatha Alzahrani, Hayaa M. Alhuthali, Amani A. Alrehaili, Abdul Hai, Mohd Imran
Electrochemical biosensors for Calreticulin in lung Canceron February 17, 2026 at 10:29 am February 17, 2026 Publication date: 1 April 2026 Source: Clinica Chimica Acta, Volume 585 Author(s): Obaid Afzal, Ali Altharawi, Mubarak A. Alamri, Manal A. Alossaimi, Abdulmalik S.A. Altamimi, Pawan Goud, Prerna Uniyal, Rakhi Mishra
Multi-omic biomarker detection in UV-induced melanomaon February 17, 2026 at 10:29 am February 17, 2026 Publication date: 1 April 2026 Source: Clinica Chimica Acta, Volume 585 Author(s): Safar M. Alqahtani, Muhammad Afzal, Obaid Afzal, Alhumaidi Alabbas, Pradnya Phalak, Kavita Goyal
Testing brigatinib in an oncological patient’s hair: Evaluation of the time of disappearance after discontinuation and interpretation of concentrations obtained in regrowing hair after total losson February 14, 2026 at 12:40 pm February 14, 2026 Publication date: 1 April 2026 Source: Clinica Chimica Acta, Volume 585 Author(s): Nadia Arbouche, Céline Traenklé, Jean-Sébastien Raul, Pascal Kintz
NMR-based metabolic measures of chronic stable angina and myocardial infarction in patients with diabetes mellituson February 13, 2026 at 11:09 am February 13, 2026 Publication date: 1 April 2026 Source: Clinica Chimica Acta, Volume 585 Author(s): Ashish Gupta, Shiridhar Kashyap, Khushbhu Meena, Deepak Kumar, Amit Gaurav, Ankit Kumar Sahu, Subhash Yadav, Sudeep Kumar, Aditya Kapoor
Exploring synergistic therapeutic potential of Erlotinib and artemisinin in non-small cell lung Cancer (NSCLC) using pharmacological networking and mathematical modelingon February 13, 2026 at 11:09 am February 13, 2026 Publication date: 1 April 2026 Source: Clinica Chimica Acta, Volume 585 Author(s): Faiqa Suleman, Tasadduq Khan, Salah A. Alshehade, Muhammad Ali, Hafiz Muhammad Irfan, Amir Shahzad, Raghdaa Hamdan Al Zarzour, Shahid Rasool
Laboratory data mining: monitoring of the local applicability of prolactin reference intervalon February 13, 2026 at 11:09 am February 13, 2026 Publication date: 1 April 2026 Source: Clinica Chimica Acta, Volume 585 Author(s): Sun Xiang, Zhu Jinwen, Wei Chen, Wang Qin
Aptasensors for NNK biomarkers in smoking-induced lung canceron February 13, 2026 at 11:09 am February 13, 2026 Publication date: 1 April 2026 Source: Clinica Chimica Acta, Volume 585 Author(s): Bandar Theyab Alenezi, Talha Jawaid, Zia Ur Rehman, Abdullah R. Alzahrani, Abdul Hai, Waseem Fatima, Prawez Alam, Abida Khan
Recent advances in phosphatases as new biomarker in personalized medicineon February 11, 2026 at 3:09 pm February 11, 2026 Publication date: 1 April 2026 Source: Clinica Chimica Acta, Volume 585 Author(s): Shreya Garge, Gayatri Gaikwad, Vasanti Suvarna
Non-coding RNAs as prognostic biomarkers in autoimmune diseaseon February 9, 2026 at 1:57 pm February 9, 2026 Publication date: 1 April 2026 Source: Clinica Chimica Acta, Volume 585 Author(s): Maryam Rahnama, Siamak Rezaeiani, Navid Ghasemzadeh, Milad Ahmadaghdami, Arezoo Mesri, Mortaza Taheri-Anganeh, Ebrahim Mazloomi
Non-coding RNAs as emerging biomarkers in melanomaon February 8, 2026 at 12:11 pm February 8, 2026 Publication date: 1 April 2026 Source: Clinica Chimica Acta, Volume 585 Author(s): Qamar Abuhassan, Mutaz Jamal Al-khreisat, R. Roopashree, Maitreyee Panda, T. Sudhakar, Vipasha Sharma, Ashish Singh Chauhan, Guzal Klebleeva
Multi-omics biomarkers in psychiatric disorders diagnosis and stratificationon February 8, 2026 at 12:11 pm February 8, 2026 Publication date: 1 April 2026 Source: Clinica Chimica Acta, Volume 585 Author(s): Seyyed Hossein Khatami, Sanam Anoosheh, Marzieh Khodaparast, Amir Maghsoudloonejad, Ehsan Dadgostar, Amir Asadi, Mahya Kaveh, Malihe Mehdinejad Haghighi
Synthetic data in the clinical laboratory: methods, applications, and future prospectson February 7, 2026 at 5:32 pm February 7, 2026 Publication date: 1 April 2026 Source: Clinica Chimica Acta, Volume 585 Author(s): Tahir S. Pillay, Barbara S. van Deventer, Siphokazi Gwiliza, Evette L. Subramoney, Chantal van Niekerk
Development of machine learning-driven non-invasive diagnostic models for idiopathic membranous nephropathy in Chinese patientson February 6, 2026 at 11:43 am February 6, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Qian Wang, Xiaolong Wang, Shibin Su, Weiguang Zhang, Quan Hong, Qiang Lyu, Shuwei Duan, Ying Zheng, Guichun Tang, Pu Chen, Jiaona Liu, Chengliang Yin, Jinlong Shi, Guangyan Cai, Xiangmei Chen, Zheyi Dong
Combining conventional hemogram and reticulocyte metrics enhances iron deficiency detection in asymptomatic individualson February 5, 2026 at 10:13 am February 5, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Mugdha Gautam, Prashant Sharma, Arnab Pal, Pulkit Rastogi, Praveen Sharma, Alka Rani Khadwal, Manu Jamwal, Minakshi Gupta, Reena Das
Comparison of manual with artificial intelligence-aided interpretation of ANA HEp-2 IIF assay patterns in a clinical diagnostics labon February 5, 2026 at 10:13 am February 5, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Jonas Schmidt, Sarina Weiß, Frithjof Blessing, Josef Blessing, Peter Schierack, Stefan Rödiger, Rico Hiemann, Dirk Roggenbuck
Bioequivalence of C-reactive protein in fingerprick blood and serum measured using the point-of-care LumiraDx test for tuberculosis diagnosis in exposed contactson February 2, 2026 at 2:00 pm February 2, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Arthur M. Chiwaya, Shima M. Abdulgader, Patricia Manjate, James Sserubiri, Bayanda Mdoda, Loide N.N. Shipingana, Dinis Nguenha, Derrick Semugenze, Marc Bañuls, Vinzeigh N. Leukes, Adam Penn-Nicholson, Achilles Katamba, Moses Joloba, Willy Ssengooba, Alberto L. García-Basteiro, Frank Cobelens, Grant Theron
Exosomal microRNA biomarkers in ovarian cancer detection: systematic review and meta-analysison February 1, 2026 at 1:08 pm February 1, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Qidan Huang, Jieping Chen, Jingsong Huang
Analysis of genetic mutation distribution and metabolic characteristics in patients with primary carnitine deficiency from the Ganzhou area, Chinaon February 1, 2026 at 1:08 pm February 1, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Xiangwen Tu, Feng Zhang, Junkun Chen, Chunlian Xie
Antibody response against HERV-K polymerase and envelope by patients with multiple sclerosison February 1, 2026 at 1:08 pm February 1, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Bruna Reimberg Flose, Kevin Cézar Nascimento Silva, Maria Aparecida Juliano, Virginia Fernandes Moça Trevisani, Carolina Nunes França, Marcelo Andreetta Corral, Luiz Henrique da Silva Nali, Marina Tiemi Shio
CRISPR/Cas9 and reproductive failure: applications, ethical challenges, and future perspectives in human germline genome editingon January 31, 2026 at 6:26 pm January 31, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Wasim Shah, Mujahid Hussain, Ayesha Serwat, Muhammad Bilal, Yousaf Raza, Abu Mansoor, Ahmad Faraz
Oxidative stress in diabetic retinopathyon January 30, 2026 at 10:22 am January 30, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Qiang Zou, Niu Niu, Leilei Sun, Xiaoyan Xu, Yu Wang, Hong Qin
Integrative metabolomics and proteomics of heat stresson January 30, 2026 at 10:22 am January 30, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Shab M. Alkhoujah, Ruba A. Zenati, Munazza Ahmed, Ahmad Y. Abuhelwa, Shereen M. Aleidi, Mohammad A.Y. Alqudah, Waseem El-Huneidi, Eman Abu-Gharbieh, Zainab M. AlShareef, Karem H. Alzoubi, Yasser Bustanji, Mohammad H. Semreen
Multi-omics biomarker detection in smoking induced COPDon January 30, 2026 at 10:22 am January 30, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Rahamat Unissa Syed, Mohammed Khaled Bin Break, Rihab Akasha, Nancy Mohammad Elafandy, Sally Hassan Abobaker, Amna abakar Suleiman Khalifa, Nayla Ahmed Mohammed Aboshouk, Afrah Nashmi Alghaythi, Lama Abdullah Altwalah, Rawabi Mohammed Menwer Aldhafeeri, Mohd Sajjad Ahmad Khan, Gaurav Gupta
Plasma ceramides decreased in Gilbert’s syndrome associated with healthy blood lipid phenotypes: A cross-sectional studyon January 28, 2026 at 3:37 pm January 28, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Haitian Yu, Chen Liang, Shan Tang, Dacheng Sheng, Jianxia Dong, Xinyue Chen, Zhongjie Hu, Zhongping Duan, Wei Hou, Sujun Zheng
Identification of diabetic kidney disease biomarkers via iTRAQ plasma proteomics analysison January 28, 2026 at 3:37 pm January 28, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Juan Yuan, Man Zhan, Xinglai Zhang, Xixiao Lin, Wei Lu, Xi Yan, Zhiyuan Liang, Yuan Sun, Minshan Su, Liming Shen, Haiying Li
Circulating biomarkers in leukemiaon January 28, 2026 at 3:37 pm January 28, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Aiyun Dong, Mehdi Jahedi Zargar, Amirhossein Mirzazadeh, Mohammad Navid Khaksari, Mobina Nazari, Niloofar Pilehvari, Hamed Soleimani Samarkhazan
The oxalobiome: unraveling the role of gut microbiota in oxalate metabolism and its implications for kidney health and disease managementon January 28, 2026 at 3:37 pm January 28, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): David Mburu, Sumeet Kumar, Yanzhe Wang, Asadoor Amirkhani Namagerdi, Karoona Bai, Bilal Ali, Ahmed Minalla, Karina Ordaya Gonzales, Khalid A. Abdelhalim
Plasma non-targeted metabolomics unveils the metabolic signatures of trans-right ventricle in pulmonary arterial hypertension associated with atrial septal defecton January 27, 2026 at 2:26 pm January 27, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Xifeng Qian, Yuanrui Deng, Tingting Guo, Xin Huang, Chaowu Yan, Xin Gao, Yan Wu, Song Hu, Jiangshan Tan, Lingtao Chong, Shengsong Zhu, Mingjie Ma, Mengting Ye, Xiaojian Wang, Jian Cao, Lu Hua
Analytical performance evaluation and reference limits establishment of a new chemiluminescence growth stimulation expressed Gene 2 Assayon January 25, 2026 at 12:26 pm January 25, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Litao Zhang, Chenbin Zhang, Xin Shu, Jiajia Zhu, Hui Wang, Ting Deng, Yisha Jing, Haiyan Liu, Zhenlu Zhang
Validating CALIPER pediatric reference intervals in a U.S. population using retrospective outpatient data and RefineRon January 24, 2026 at 5:32 pm January 24, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Jillian Kodger, Thomas J.S. Durant, Nalan Yurtsever, Joe M. El-Khoury
ALT-triggered reflex AST testing in health check-ups: A decision curve analysison January 22, 2026 at 9:35 am January 22, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Shu-Mei Bai, Xu-Xiao Guo, Guo-Ming Zhang
Exosome biosensors for detection of Lung canceron January 22, 2026 at 9:35 am January 22, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Obaid Afzal, Pavan Goud, Kavita Goyal, Ali Altharawi, Mubarak A. Alamri, Manal A. Alossaimi, Abdulmalik S.A. Altamimi, Surya Nath Pandey
Simultaneous quantification of acetylsalicylic acid, clopidogrel, ticagrelor and their major metabolites in human plasma by liquid chromatography–tandem mass spectrometryon January 21, 2026 at 3:02 pm January 21, 2026 Publication date: 15 March 2026 Source: Clinica Chimica Acta, Volume 584 Author(s): Wenqiang Wang, Lijiao Zhang, Ciren Baima, Shenghao Gao, Xiaoyu Sun, Xiaoguang Xu, Yunfeng Cao
Point-of-care testing in ischemic strokeon January 20, 2026 at 1:54 pm January 20, 2026 Publication date: 1 March 2026 Source: Clinica Chimica Acta, Volume 583 Author(s): Ziqi Han, Yunping Wu, Ruikang Sun, Wen Zhao, He Liang, Lu Wang, Yalin Xi, Yi Liu
GDF-15 as an integrative cardiometabolic biomarkeron January 19, 2026 at 11:58 am January 19, 2026 Publication date: 1 March 2026 Source: Clinica Chimica Acta, Volume 583 Author(s): Obaid Afzal, Muhammad Afzal, Nawaid Hussain Khan, Ali Altharawi, Mubarak A. Alamri, Manal A. Alossaimi, Abdulmalik S.A. Altamimi, Pavan Goud
Phenotype-genotype correlation in a cohort of 15 patients with hereditary ichthyosison January 18, 2026 at 10:31 am January 18, 2026 Publication date: 1 March 2026 Source: Clinica Chimica Acta, Volume 583 Author(s): Yu-jie Ma, Jing Li, Yang Liu, Tian-ying Wei, Jia-en Liu, Jing Zhang, Hua-ying Hu, Kai Yang
Tissue polypeptide antigen as a non-invasive bladder Cancer biomarkeron January 18, 2026 at 10:31 am January 18, 2026 Publication date: 1 March 2026 Source: Clinica Chimica Acta, Volume 583 Author(s): Neeraj Kumar Fuloria, Kamal Narain, Anupam Biswas, Padmashini Gnanam, Satish Vasanth Dhandapani, Sangita Biswas, Sumita Bhatia, Shivkanya Fuloria
The commutability of thyroid-stimulating hormone international reference preparations plays an important role in metrological traceabilityon January 17, 2026 at 9:49 am January 17, 2026 Publication date: 1 March 2026 Source: Clinica Chimica Acta, Volume 583 Author(s): Shunli Zhang, Fei Cheng, Hua Wang, Mo Wang, Rui Zhang, Yuhong Yue, Qingtao Wang
NMR-based metabolomics reveals distinct metabolic profiles in juvenile systemic lupus erythematosus and juvenile idiopathic arthritison January 17, 2026 at 9:49 am January 17, 2026 Publication date: 1 March 2026 Source: Clinica Chimica Acta, Volume 583 Author(s): Jeferson S. Ursulino, Edmilson R.R. Junior, Larissa S. Pinto, Paula Sandrin-Garcia, Denise Q. Nascimento, Thiago S. Fragoso, Thiago M. Aquino
Evaluation of MASSARRAY technique in detecting mitochondrial disease mutationson January 14, 2026 at 11:47 am January 14, 2026 Publication date: 1 March 2026 Source: Clinica Chimica Acta, Volume 583 Author(s): Nahuda Chetu, Preyaporn Onsod, Budsaba Rerkamnuaychoke, Teerapong Siriboonpiputtana, Takol Chareonsirisuthigul
Clinical utilization of beta-hydroxybutyrate and comparison with urine ketones in a quaternary care health systemon January 14, 2026 at 11:47 am January 14, 2026 Publication date: 1 March 2026 Source: Clinica Chimica Acta, Volume 583 Author(s): Maxwell L. Harsha, Mary Ann Ness, Mark A. Marzinke
