Determination of HE4 in pleural fluid and ratio: considerations and diagnostic performance for malignant pleural effusionElisa Nuez-Zaragozaon May 15, 2026 at 10:00 am May 16, 2026 Adv Lab Med. 2026 Apr 7;7(2):105-115. doi: 10.1515/almed-2025-0175. eCollection 2026 Jun. ABSTRACT OBJECTIVES: The objectives of this study included assessing the diagnostic performance of HE4 in malignant pleural effusions (MPEs) …
Read more Utility of the I-index as a pre-screening tool for total bilirubin testing: a retrospective study in a regional hospitalAmanda Jiménez Garcíaon May 15, 2026 at 10:00 am May 16, 2026 Adv Lab Med. 2026 Jan 22;7(2):153-155. doi: 10.1515/almed-2025-0161. eCollection 2026 Jun. ABSTRACT OBJECTIVES: This study evaluates the efficacy of the icteric index as a pre-screening tool for hyperbilirubinemia in adult …
Read more Anti-GBM pulmonary-renal syndrome: when the laboratory makes the differenceCarmen Frías Ruizon May 15, 2026 at 10:00 am May 16, 2026 Adv Lab Med. 2026 Jan 12;7(2):160-162. doi: 10.1515/almed-2025-0099. eCollection 2026 Jun. ABSTRACT OBJECTIVES: Pulmonary-renal syndrome (PRS) is a serious condition characterized by concurrent alveolar hemorrhage and rapidly progressive glomerulonephritis. One …
Read more High sensitive troponin T elevation in an oncology patient on treatment with PembrolizumabAlberto Alcalde Moraleson May 15, 2026 at 10:00 am May 16, 2026 Adv Lab Med. 2025 Nov 25;7(2):156-159. doi: 10.1515/almed-2025-0148. eCollection 2026 Jun. ABSTRACT OBJECTIVES: Troponins are a complex of three proteins that play a key role in the contraction of striated …
Read more The evolving role of PSA in prostate cancer screening: revisiting the evidence in the era of personalized medicineXavier Filellaon May 15, 2026 at 10:00 am May 16, 2026 Adv Lab Med. 2026 Jan 28;7(2):81-89. doi: 10.1515/almed-2025-0187. eCollection 2026 Jun. ABSTRACT Prostate-specific antigen (PSA) is a widely available and analytically robust biomarker, but its role in prostate cancer (PCa) …
Read more An algorithm to predict intrathecal IgM synthesis in multiple sclerosis patients: optimizing the use of oligoclonal band testingJordi Tortosa-Carrereson May 15, 2026 at 10:00 am May 16, 2026 Adv Lab Med. 2025 Dec 8;7(2):148-152. doi: 10.1515/almed-2025-0098. eCollection 2026 Jun. ABSTRACT OBJECTIVES: We aimed to develop a simple, cost-effective algorithm to predict the presence of oligoclonal IgM bands (OCMB) …
Read more Carcinocythemia detection in peripheral blood smears: a literature reviewJavier Lagunaon May 15, 2026 at 10:00 am May 16, 2026 Adv Lab Med. 2026 Mar 16;7(2):90-104. doi: 10.1515/almed-2025-0169. eCollection 2026 Jun. ABSTRACT Carcinocythemia, or carcinoma cell leukemia, is a rare but striking manifestation of advanced malignancy in which circulating tumor …
Read more Pharmacogenetic biomarkers for predicting therapeutic response to JAK inhibitors in rheumatoid arthritisChamaida Plasencia-Rodríguezon May 15, 2026 at 10:00 am May 16, 2026 Adv Lab Med. 2026 Apr 23;7(2):124-131. doi: 10.1515/almed-2025-0180. eCollection 2026 Jun. ABSTRACT OBJECTIVES: Rheumatoid arthritis (RA) is a chronic inflammatory disease of immune-mediated origin. Janus kinase inhibitors (JAK inhibitors) have …
Read more Exploring Sex-Specific High-Sensitivity Cardiac Troponin Thresholds for Rule-Out of Non-ST-Elevation Myocardial Infarction May 16, 2026 Clin Chem. 2026 May 15:hvag030. doi: 10.1093/clinchem/hvag030. Online ahead of print. ABSTRACT BACKGROUND: Sex-specific diagnostic thresholds for high-sensitivity cardiac troponin (hs-cTn) assays are recommended by international guidelines for the diagnosis …
Read more Correction to: Cardiac Biomarker Kinetics in Patients after Coronary Artery Bypass Grafting with an Uncomplicated Course May 16, 2026 Clin Chem. 2026 May 12:hvag054. doi: 10.1093/clinchem/hvag054. Online ahead of print. NO ABSTRACT PMID:42118966 | DOI:10.1093/clinchem/hvag054
First-trimester free thyroxine as an independent predictor of gestational diabetes mellitus: a retrospective cohort studyThu T T Doon May 15, 2026 at 10:00 am May 16, 2026 Adv Lab Med. 2026 Apr 28;7(2):132-139. doi: 10.1515/almed-2026-0007. eCollection 2026 Jun. ABSTRACT OBJECTIVES: Gestational diabetes mellitus (GDM) and thyroid dysfunction are two common endocrine diseases during pregnancy, both of which …
Read more Comparison of capillary and venous hemoglobin determination among school-age children: insights from Zanzibar, TanzaniaKaunara Azizion May 15, 2026 at 10:00 am May 16, 2026 Adv Lab Med. 2026 Apr 15;7(2):140-147. doi: 10.1515/almed-2025-0053. eCollection 2026 Jun. ABSTRACT OBJECTIVES: There is apprehension regarding the agreement between capillary and venous hemoglobin (Hb) concentrations, which may have far-reaching …
Read more 5th National Point-Of-Care Testing Symposiumon May 15, 2026 at 10:00 am May 16, 2026 Clin Chem Lab Med. 2026 May 18. doi: 10.1515/cclm-2026-0532. Online ahead of print. NO ABSTRACT PMID:42138963 | DOI:10.1515/cclm-2026-0532
Comprehensive assessment of innovative immunoassays for the detection of myositis specific antibodiesIvo Rimann-Langejuergenon May 14, 2026 at 10:00 am May 16, 2026 Clin Chem Lab Med. 2026 May 15. doi: 10.1515/cclm-2026-0179. Online ahead of print. ABSTRACT OBJECTIVES: Myositis specific antibodies (MSA) are important in the diagnosis of idiopathic inflammatory myopathies (IIM). In …
Read more Combined measurement uncertainty of HbA1c and glucose using ISO 20914:2019 and outcome-based simulationEmine Feyza Yurton May 14, 2026 at 10:00 am May 16, 2026 Clin Chem Lab Med. 2026 May 15. doi: 10.1515/cclm-2026-0388. Online ahead of print. ABSTRACT OBJECTIVES: This study aimed to calculate the measurement uncertainty (MU) of HbA1c and glucose according to …
Read more Patient-centric capillary dried blood spot sampling for tacrolimus and creatinine monitoring in clinical practiceHanna De Baetson May 13, 2026 at 10:00 am May 16, 2026 Clin Chem Lab Med. 2026 May 14. doi: 10.1515/cclm-2026-0320. Online ahead of print. ABSTRACT OBJECTIVES: Therapeutic drug monitoring (TDM) of tacrolimus is essential due to its high inter- and intra-patient …
Read more Effect of heparin plasma storage at -20 °C or 4 °C on lipoprotein(a) risk stratificationJorik H Ameszon May 13, 2026 at 10:00 am May 16, 2026 Clin Chem Lab Med. 2026 May 14. doi: 10.1515/cclm-2026-0457. Online ahead of print. NO ABSTRACT PMID:42126325 | DOI:10.1515/cclm-2026-0457
Optimising newborn screening for galactosaemia: reclassifying GALE and GALM deficiencies as non-target conditions to improve specificityDoris Wongon May 13, 2026 at 10:00 am May 16, 2026 Clin Chem Lab Med. 2026 May 14. doi: 10.1515/cclm-2026-0419. Online ahead of print. ABSTRACT OBJECTIVES: Traditionally, neonates were screened for classical galactosaemia in 4 of the 5 jurisdictions in Australia …
Read more Characterizing variation in laboratory medicine data: a comparative analysis of standard deviation and coefficient of variationAbdurrahman Coskunon May 13, 2026 at 10:00 am May 16, 2026 Clin Chem Lab Med. 2026 May 14. doi: 10.1515/cclm-2026-0672. Online ahead of print. NO ABSTRACT PMID:42126015 | DOI:10.1515/cclm-2026-0672
Impact of delayed centrifugation on the stability of 32 biochemical analytes in blood samples collected in serum gel tubes and stored at room temperatureMaría Sanz-Felision May 12, 2026 at 10:00 am May 16, 2026 Clin Chem Lab Med. 2026 Feb 23;64(4):968-969. doi: 10.1515/cclm-2026-0081. Print 2026 Mar 26. NO ABSTRACT PMID:42118557 | DOI:10.1515/cclm-2026-0081
The first case of Teclistamab interference with serum electrophoresis and immunofixationKamran Kadkhodaon May 12, 2026 at 10:00 am May 16, 2026 Clin Chem Lab Med. 2025 Apr 17;63(7):1453. doi: 10.1515/cclm-2025-0446. Print 2025 Jun 26. NO ABSTRACT PMID:42118546 | DOI:10.1515/cclm-2025-0446
The complete blood count: data or clinical information?Mario Plebanion May 12, 2026 at 10:00 am May 16, 2026 Clin Chem Lab Med. 2026 May 13. doi: 10.1515/cclm-2026-0590. Online ahead of print. ABSTRACT Harmonization in laboratory medicine is increasingly recognized as a fundamental requirement to ensure interchangeable laboratory information, …
Read more Biological variation of serum Anti-Müllerian Hormone in healthy adult menon May 16, 2026 at 5:31 am May 16, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Rumeysa Betül Kılınçer, Ayşen Caniklioğlu, Müjgan Ercan
Both of coagulopathy and neutrophil extracellular trap markers are associated with poor prognosis of dabie bandavirus infectionon May 16, 2026 at 5:31 am May 16, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Fan Bai, Zekai Lei, Huan Bai, Dengju Li, Ning Tang
Establishment of reference intervals for 41 serum biochemical analytes in healthy Chinese childrenon May 16, 2026 at 5:31 am May 16, 2026 Publication date: July 2026 Source: Practical Laboratory Medicine, Volume 50 Author(s): Qinlan Liu, Xiufa Zhang, Ling Zhuang, Yidan Wang, Xian Chen, Feng Wang
Utilization of HLA-B27 genotyping in a mixed primary–hospital care (2023–2025): Test yield by requesting service, demographic predictors, and prevention of unnecessary duplicate genetic testingon May 16, 2026 at 5:31 am May 16, 2026 Publication date: August 2026 Source: Clinical Biochemistry, Volume 144 Author(s): Alexandre Xabier Obelleiro Campos, Cristian Malagón, Marta Ribera, Rafael Fernández, Mónica Pedrique
Bridging innovation and implementation in laboratory medicine: insights from a global survey on unmet needs and emerging technologieson May 16, 2026 at 5:31 am May 16, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Damien Gruson, Bernard Gouget, Serafeim Karathanos, Ronda Greaves, Yan Liu, Sven Ebert, Swarup Shah
Circulating suPAR in autoimmune liver diseases: advancing global noninvasive fibrosis and immune profilingon May 16, 2026 at 5:31 am May 16, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Rajesh Prasad Jayaswal
Closing the evidence gap: Capillary high-sensitivity troponin I verification in an African population using point of careon May 16, 2026 at 5:31 am May 16, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Maseti Amvuyele Ann, Jacob Doreen, Khoza Siyabonga, Chikomba Chemedzai
Reply to: Personalized reference intervals based on biological variation: a critical evaluation of strengths and limitationsWerner Wosniokon May 10, 2026 at 10:00 am May 11, 2026 Clin Chem Lab Med. 2026 May 11. doi: 10.1515/cclm-2026-0554. Online ahead of print. NO ABSTRACT PMID:42107068 | DOI:10.1515/cclm-2026-0554
A model to increase automation and support reliable interpretation of clinical chemistry testsAlessandra Faldaon May 10, 2026 at 10:00 am May 11, 2026 Clin Chem Lab Med. 2026 May 11. doi: 10.1515/cclm-2025-1727. Online ahead of print. ABSTRACT OBJECTIVES: Pathological conditions may result in clinical chemical values exceeding the linearity range of laboratory methods. …
Read more Rethinking atherogenic risk: is apolipoprotein B a better biomarker?Giuseppe Lippion May 9, 2026 at 10:00 am May 11, 2026 Clin Chem Lab Med. 2026 May 11. doi: 10.1515/cclm-2026-0624. Online ahead of print. NO ABSTRACT PMID:42106163 | DOI:10.1515/cclm-2026-0624
Limitations to the development of Milan model 1b analytical performance specificationsGraham Ross Dallas Joneson May 9, 2026 at 10:00 am May 11, 2026 Clin Chem Lab Med. 2026 May 11. doi: 10.1515/cclm-2026-0377. Online ahead of print. ABSTRACT A widely accepted approach to setting Analytical Performance Specifications (APS) in laboratory medicine is the Milan …
Read more Factors associated with analytical errors in blood chemistry testsHyunjung Kimon May 9, 2026 at 10:00 am May 11, 2026 Clin Chem Lab Med. 2026 May 11. doi: 10.1515/cclm-2026-0153. Online ahead of print. ABSTRACT OBJECTIVES: Few studies have systematically evaluated the factors contributing to laboratory errors in the analytical phase. …
Read more Emerging biomarkers in IgA nephropathy, membranous nephropathy, and lupus nephritison May 11, 2026 at 2:32 pm May 11, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Hiroki Kobayashi, Yusuke Murata, Yurie Akiya, Tomomi Matsuoka, Hiromasa Otsuka, Akiko Tsunemi, Yoshihiro Nakamura, Masaki Azuma, Masanori Abe …
Read more Exploring the role of circulating glial fibrillary acidic protein and neurofilament light chain in myasthenia gravison May 11, 2026 at 2:32 pm May 11, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Caterina Maria Gambino, Luisa Agnello, Concetta Scazzone, Martina Tamburello, Anna Masucci, Roberta Vassallo, Vincenzo Di Stefano, Filippo Brighina, …
Read more Chemical and biochemical derivates of trans-3-methylglutaconyl CoA: A molecular labyrinthon May 11, 2026 at 2:32 pm May 11, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Elizabeth A. Jennings, Dylan E. Jones, Robert O. Ryan
Rapid and highly sensitive detection of MYD88/CXCR4 mutations in Waldenström macroglobulinemia by MAS-qPCR: A pilot studyon May 11, 2026 at 2:32 pm May 11, 2026 Publication date: August 2026 Source: Clinical Biochemistry, Volume 144 Author(s): Yuki Kunimune, Mitsuaki Nishioka, Haruka Namba, Kimika Todaka, Tomohiro Fujii, Nayu Kiso, Yukiko Nakahara, Kanae Shinkawa, Yumiko Kumano, Masaki Kodama, …
Read more Serial monitoring of cytokine profile, liver function, and hematological biomarkers in severe CRS and CLS following CAR-T cell therapy for relapsed hepatocellular carcinoma: a case reporton May 11, 2026 at 2:32 pm May 11, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Minle Wu, Wei Guo, Beili Wang, Meixiu Gu, Chong Wang
Analytical performance evaluation and method comparison of the 1copy BCR::ABL1 qPCR assay for monitoring chronic myeloid leukemiaon May 11, 2026 at 2:32 pm May 11, 2026 Publication date: Available online 9 May 2026 Source: Practical Laboratory Medicine Author(s): Hyerin Kim, Do Young Kim, Hyerim Kim
Analytical agreement and platform-specific decision thresholds for plasma p-tau217 measured on Lumipulse G600II and Cobas e801 in a paired CSF-plasma cohortMaría Martínez-Bujidoson May 5, 2026 at 10:00 am May 10, 2026 Clin Chem Lab Med. 2026 May 5. doi: 10.1515/cclm-2026-0395. Online ahead of print. ABSTRACT OBJECTIVES: Plasma phosphorylated tau at threonine 217 (p-tau217) has emerged as a highly accurate blood-based biomarker …
Read more Inter-Instrument Imprecision Complements Bias in Evaluating LDL-C Method Performance May 10, 2026 Clin Chem. 2026 May 7:hvag042. doi: 10.1093/clinchem/hvag042. Online ahead of print. NO ABSTRACT PMID:42096656 | DOI:10.1093/clinchem/hvag042
In Reply to Inter-Instrument Imprecision Complements Bias in Evaluating LDL-C Method Performance May 10, 2026 Clin Chem. 2026 May 7:hvag043. doi: 10.1093/clinchem/hvag043. Online ahead of print. NO ABSTRACT PMID:42095830 | DOI:10.1093/clinchem/hvag043
Pseudovirus reference material and RT-digital PCR reference method for the quantification of human rhinovirus RNA with metrological traceabilityHuijie Lion May 6, 2026 at 10:00 am May 10, 2026 Clin Chem Lab Med. 2026 May 7. doi: 10.1515/cclm-2025-1137. Online ahead of print. ABSTRACT OBJECTIVES: This study developed a pseudoviral human rhinovirus (HRV) reference material using pseudovirus technology and integrating …
Read more EFLM position statement on the proposed 2025/0404(COD) IVDR Amendment of Article 5.5Christa Cobbaerton May 6, 2026 at 10:00 am May 10, 2026 Clin Chem Lab Med. 2026 May 7. doi: 10.1515/cclm-2026-0580. Online ahead of print. ABSTRACT Regulation (EU) 2017/746 on in vitro diagnostic medical devices (IVDR) was introduced to enhance patient safety …
Read more From research to reality: real-world effectiveness of point-of-care testing in the emergency departmentSalomón Martin-Pérezon May 5, 2026 at 10:00 am May 10, 2026 Clin Chem Lab Med. 2026 May 6. doi: 10.1515/cclm-2026-0289. Online ahead of print. ABSTRACT OBJECTIVES: To evaluate the real-world impact of Point-of-Care Testing on care timeliness and patient flow in …
Read more Corrigendum to “Biological variability of lipoprotein-associated phospholipase A2 activity in healthy individuals” [Clin. Biochem. 50 (2017) 347–349]on May 10, 2026 at 5:20 am May 10, 2026 Publication date: June 2026 Source: Clinical Biochemistry, Volume 143 Author(s): Leslie J. Donato, Jeffrey W. Meeusen, Sarah M. Jenkins, Stacy J. Hartman, Amy K. Saenger, Nikola A. Baumann, Darci R. …
Read more Multi-omics identification of aging-related diagnostic genes and therapeutic targets in renal fibrosison May 10, 2026 at 5:20 am May 10, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Supei Yin, Jiaojiao Gong, Dongli Huang, Diguang Wen, Zhihui Quan, Chengmei Shu
The role of coagulation waveform kinetic parameters in the early diagnosis and prognosis of coagulopathy in hepatitis and cirrhosison May 10, 2026 at 5:20 am May 10, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Qinglan Lu, Weijie Zhou, Min Pan, Shuliang Hua, Dongrong Luo, Lina Yang, Xiaoxuan Zhou, Jinjiu Huang, Rukai Wu, …
Read more Harmonizing sample collection quality indicator monitoring via an informatics platform in a regional medical laboratory networkon May 10, 2026 at 5:20 am May 10, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Dayang Chen, Yingying Zhang, Liya Liu, Ruiwei Jiang, Qingshan Ma, Hui Wu, Xiuming Zhang, Tong Ou
Automated ICAP AC-30/AC-2 discrimination on HEp-2 indirect immunofluorescence: development and clinical validation of a retrieval-based diagnostic systemon May 10, 2026 at 5:20 am May 10, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Changmeng Wu, Kechi Fang, Chuan Li, Yu Li, Jing Wang
Free light chain EQA: Analytical variability with clinical consequences – Data from 25 Italian EQA exercises (2021–2025)on May 10, 2026 at 5:20 am May 10, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Fabio Pasotti, Simona Da Molin, Tiziana Bosoni, Giovanna Azzarà, Giuseppa Liga, Giuseppe Moriello, Barbara Zaccaria, Sabrina Buoro
Analytical approaches for the isolation and characterisation of circulating tumour cells in clinical practiceon May 10, 2026 at 5:20 am May 10, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Laura Martín-Carbajo, Juan Pablo Hervás-Pérez, María Moreno-Guzmán, Marta Sánchez-Paniagua
DNA aptamer based detection of thyroid stimulating hormone for point of care testingon May 10, 2026 at 5:20 am May 10, 2026 Publication date: 15 August 2026 Source: Clinica Chimica Acta, Volume 590 Author(s): Rulli Rosandi, Achmad Rudijanto, Aulanni’am, Hidayat Sujuti
NT-proBNP and its correlation to left ventricular ejection fraction and heart failure – The DEMONSTRATE databaseMorgan Lundgren, Peter Ridefelt, Maria K Svensson, Emil Hagström, Thomas Cars, Anders Larsson1Department of Medical Sciences, Clinical Chemistry, 59592Uppsala University, Uppsala, Sweden2Department of Medical Sciences, Renal Medicine, 59592Uppsala University, Uppsala, Sweden3Uppsala Clinical Research Centre, Uppsala, Sweden4Department of Medical Sciences, Cardiology, 83048Uppsala University, Uppsala, Sweden5Sence Research AB, Uppsala, Swedenon November 17, 2025 at 5:23 am May 10, 2026 Annals of Clinical Biochemistry, Ahead of Print. BackgroundMeasurement of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and left ventricular ejection fraction (LVEF) are used in diagnosing heart failure (HF). The main aim …
Read more Direct serum biomarkers of liver fibrosis in metabolic dysfunction-associated steatotic liver disease: A scoping reviewon May 10, 2026 at 5:20 am May 10, 2026 Publication date: August 2026 Source: Clinical Biochemistry, Volume 144 Author(s): Valentina Pecoraro, Fabio Nascimbeni, Filippo Gabrielli, Tommaso Fasano, Tommaso Trenti
Predicting poor prognosis risk after endovascular thrombectomy for acute ischemic stroke: combination of TMAO and white matter lesionsChu Zhou Qi-Yang Yuan Yu-Kun Wang Chong-ke Zhong Yao-Wu Liu Fen-Fang Gao Rong-Rong Liu Wei Li Ruo-Yu Qin Shi-Guang Zhu De-qin Geng a Xuzhou Medical University, Xuzhou, Chinab Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, Chinac Department of Neurology, Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, Chinad Department of Neurology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Chinaon April 21, 2026 at 4:56 am May 10, 2026 Volume 86, Issue 3, MAY 2026, Page 224-236.
The association between ionized and total magnesium in critically ill patients: a prospective cohort studyEyrun A. Kristinsdottir Svajunas Statkevicius Martin I. Sigurdsson Fredrik Hansson Marcus E. Broman a Department of Perioperative and Intensive Care, Skåne University Hospital, Lund, Swedenb Faculty of Medicine, Lund University, Lund, Swedenc Department of Anaesthesia and Intensive Care, Perioperative Services at Landspitali, the National University Hospital of Icelandd Faculty of Medicine, University of Iceland, Reykjavik, Icelande Integrative Research Laboratories Sweden AB, Göteborg, Swedenon March 14, 2026 at 2:22 am May 10, 2026 Volume 86, Issue 3, MAY 2026, Page 237-244.
Reference intervals for lysosomal glucocerebrosidase activity in the healthy populationVinu Rajendran Divya T. Nair Prinu Jose Shouvik Basu M. L. Saju Geetha Mandagini Cibin T. Raghavan Syam Krishnan Srinivas Gopala Madhusoodanan Urulangodi a Department of Transfusion Medicine, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, Indiab Department of Biochemistry, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, Indiac Achutha Menon Centre for Health Science Studies, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, Indiad Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Comprehensive Care Centre for Movement Disorders, Thiruvananthapuram, Kerala, Indiaon March 15, 2026 at 4:23 am May 10, 2026 Volume 86, Issue 3, MAY 2026, Page 245-252.
Evaluation of analytical equivalence between Ampulab and BD Vacutainer blood collection tubes across clinical chemistry, immunoassay, hematology, and coagulation panelsImseok Kang Byoung-Sun Mun Jung Yoon Jung Ah Kwon Chae Seung Lim Ha Nui Kim Soo-Young Yoon Department of Laboratory Medicine, Korea University College of Medicine, Seoul, Koreaon May 5, 2026 at 4:05 am May 10, 2026 Volume 86, Issue 3, MAY 2026, Page 273-284.
Recommendation on quality assurance of pneumatic transportation systems an opinion paper from the Nordic preanalytical scientific working groupJonna Pelanti Britta Willman Anna Linko-Parvinen Mads Nybo a Labquality, Helsinki, Finlandb Department of Medical Biosciences, Clinical Chemistry, Umeå University, Umeå, Swedenc Department of Clinical Chemistry, University of Turku, and Tyks Laboratories, Clinical Chemistry, Turku University Hospital, Turku, Finlandd Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmarkon April 16, 2026 at 6:34 am May 10, 2026 Volume 86, Issue 3, MAY 2026, Page 293-297.
Measurements of plasma melatonin by rapid LC-MS/MS enables insight into diurnal variation in healthy humansJakob Albrethsen Jonas Korsgaard Andreasen Jennifer Anton Henriette P. Sennels Henrik L. Jørgensen Jens Hannibal Ditte Hermann Nicolai J. Wewer Albrechtsen a Department of Clinical Biochemistry, Copenhagen University Hospital – Bispebjerg and Frederiksberg, Copenhagen, Denmarkb Department of Clinical Biochemistry, Copenhagen University Hospital – Hvidovre, Hvidovre, Denmarkc Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmarkon April 20, 2026 at 6:14 am May 10, 2026 Volume 86, Issue 3, MAY 2026, Page 306-312.
Associations between snus use and concentrations of CRP, 25(OH)D and testosterone: a population-based studyMarja Lisa Byhamre Stefan Blankenberg Per Dahlqvist Marie Eriksson Viktor Oskarsson Stefan Söderberg Tanja Zeller Patrik Wennberg a Department of Public Health and Clinical Medicine, Family Medicine, Umeå University, Umeå, Swedenb Department of Epidemiology and Global Health, Umeå University, Umeå, Swedenc University Heart and Vascular Center Hamburg, Medical University Hamburg, German Center of Cardiovascular Research, Partner site Hamburg, Kiel, Lübeck, Hamburg, Germanyd Department of Public Health and Clinical Medicine, Medicine, Umeå University, Umeå, Swedene Department of Statistics, Umeå School of Business, Economics, and Statistics, Umeå University, Umeå, Swedenf Department of Public Health and Clinical Medicine, Piteå Research Unit – Norrbotten, Umeå University, Umeå, Swedeng Institute of Cardiogenetics, University Medical Center Schleswig-Holstein, University of Lübeck, Germanyh German Center for Cardiovascular Research, Partner Site North, Lübeck, Germanyon March 31, 2026 at 11:00 am May 10, 2026 Volume 86, Issue 3, MAY 2026, Page 253-262.
Performance evaluation of the new Sysmex XR9000 hematology system in a clinical setting in comparison with Sysmex XN9100Maria Boysen Sandberg Pernille Just Vinholt Department of Clinical Biochemistry, Odense University Hospital, Odense C, Denmarkon April 21, 2026 at 5:08 am May 10, 2026 Volume 86, Issue 3, MAY 2026, Page 263-272.
Less testing, more yield: a multicomponent intervention halves inpatient biochemistryMalene S. Jacobsen Andi E. Albertsen Christian Trolle a Medical Diagnostic Centre, Regional Hospital Central Jutland, Denmarkb Department of Cardiology, Regional Hospital Central Jutland, Denmarkc University Research Clinic for Innovative Patient Pathways, Regional Hospital Central Jutlandd Institute of Clinical Medicine, Aarhus University, Denmarkon April 19, 2026 at 6:13 am May 10, 2026 Volume 86, Issue 3, MAY 2026, Page 285-292.
Diurnal fluctuations in thyroid hormones – the Bispebjerg study of diurnal variationsBakhtawar Zahra Rabab Christian Zinck Jensen Henrik Løvendahl Jørgensen Henriette Pia Sennels a Department of Clinical Biochemistry, Copenhagen University Hospital – Amager and Hvidovre, Hvidovre, Denmarkb Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmarkc Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmarkd Department of Clinical Biochemistry, Copenhagen University Hospital – Bispebjerg and Frederiksberg, Copenhagen, Denmarkon April 21, 2026 at 4:42 am May 10, 2026 Volume 86, Issue 3, MAY 2026, Page 298-305.
Performance Validation and Clinical Concordance of a Novel Fully Automated Immunoassay System for Five Tumor Markers: A Comparative Study with an International Reference Platformon May 10, 2026 at 5:20 am May 10, 2026 Publication date: Available online 7 May 2026 Source: Practical Laboratory Medicine Author(s): Ruobing Wang, Jianmin Liu, Ting Cao, Xiaohan Qiao, Xinyu Deng, Tianhuan Xiong, Yaoyao Yang, Junge Zhang, Min Li, …
Read more Persistent red fluorescence interference in anti-PLA2R indirect immunofluorescence assays associated with liposomal doxorubicinon May 10, 2026 at 5:20 am May 10, 2026 Publication date: August 2026 Source: Clinical Biochemistry, Volume 144 Author(s): Stéphane Lopes-Paciencia, Nicolas J. Caron, Charleen Salesse, Jean-Sébastien Claveau, Louis-Philippe Laurin, Karim Benkirane
Verification of pleural fluid pH on radiometer ABL 90 flex plus blood gas analyzeron May 10, 2026 at 5:20 am May 10, 2026 Publication date: August 2026 Source: Clinical Biochemistry, Volume 144 Author(s): Vinita Thakur, Olatunji Anthony Akerele, Edward Randell
Commentary on Bullwinkle’s Revenge: From Moose Roast to Nocturnal Urticaria May 5, 2026 Clin Chem. 2026 May 5;72(5):532-533. doi: 10.1093/clinchem/hvag027. NO ABSTRACT PMID:42084431 | DOI:10.1093/clinchem/hvag027
Commentary on Bullwinkle’s Revenge: From Moose Roast to Nocturnal Urticaria May 5, 2026 Clin Chem. 2026 May 5;72(5):533-534. doi: 10.1093/clinchem/hvaf188. NO ABSTRACT PMID:42084430 | DOI:10.1093/clinchem/hvaf188
Plasmids for the Modern Microbe May 5, 2026 Clin Chem. 2026 May 5;72(5):613-614. doi: 10.1093/clinchem/hvag016. NO ABSTRACT PMID:42084429 | DOI:10.1093/clinchem/hvag016
Bullwinkle’s Revenge: From Moose Roast to Nocturnal Urticaria May 5, 2026 Clin Chem. 2026 May 5;72(5):529-532. doi: 10.1093/clinchem/hvaf183. NO ABSTRACT PMID:42084432 | DOI:10.1093/clinchem/hvaf183
Capillary dried blood microsampling is not suited for dihydropyrimidine dehydrogenase (DPD) phenotypingKevin Vandenbrouckeon May 5, 2026 at 10:00 am May 5, 2026 Clin Chem Lab Med. 2026 May 6. doi: 10.1515/cclm-2026-0146. Online ahead of print. ABSTRACT OBJECTIVES: Dihydropyrimidine dehydrogenase (DPD) phenotyping through uracil and dihydrouracil determination is a well-established approach to identify …
Read more Essential laboratory tests in emergencies; on behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Committee on Preparation of Laboratories for Emergencies (C-PLE)Giuseppe Lippion May 5, 2026 at 10:00 am May 5, 2026 Clin Chem Lab Med. 2026 May 6. doi: 10.1515/cclm-2026-0577. Online ahead of print. ABSTRACT This article aims to define a minimum panel of essential laboratory tests to be used in …
Read more Analytical performance of the VITA™ point-of-care CD4 enumeration assayon May 5, 2026 at 8:29 pm May 5, 2026 Publication date: 15 July 2026 Source: Clinica Chimica Acta, Volume 589 Author(s): Chui Mei Ong, Aquiles R. Henriquez-Trujillo, Melissa Alamillo, Wei Huang, Ed Goldberg, Dorien Van den Bossche, Tinne Gils, …
Read more Impact of angiotensin receptor–neprilysin inhibitor therapy on urinary C-peptide measurements: A potential pitfall in the β-cell function assessmenton May 5, 2026 at 8:29 pm May 5, 2026 Publication date: 15 July 2026 Source: Clinica Chimica Acta, Volume 589 Author(s): Satoshi Fujimura, Yoko Usami, Takashi Sekido, Yuka Miyamoto, Akari Yamamoto, Harue Suzuki, Riho Shimizu, Nau Ishimine
Determination of cytomegalovirus IgG antibodies using stable element labeling and inductively coupled plasma mass spectrometry: Further evidence of the feasibility of antibody detectionon May 4, 2026 at 7:27 pm May 4, 2026 Publication date: 15 July 2026 Source: Clinica Chimica Acta, Volume 589 Author(s): Wencan Jiang, Haoran Li, Gongwei Sun, Ruimin Ma, Runzhuo Wu, Linfeng Sheng, Yijun Shi, Guojun Zhang
Automated detection of mulberry bodies in urinary sediment for non-invasive Fabry disease screeningHiroshi Yamanakaon May 1, 2026 at 10:00 am May 3, 2026 Clin Chem Lab Med. 2026 Apr 30. doi: 10.1515/cclm-2026-0345. Online ahead of print. NO ABSTRACT PMID:42066038 | DOI:10.1515/cclm-2026-0345
Comparison of pre-analytical properties of blood collection systems for the diagnosis of diabetes mellituson May 3, 2026 at 11:25 am May 3, 2026 Publication date: July 2026 Source: Practical Laboratory Medicine, Volume 50 Author(s): Juliane Flindt, Michael Radziewitz, Andreas Müller, Sofie Harnack, Antje Schwarz
Multicenter comparison of three automated procalcitonin (PCT) assays and commutability evaluation of EQA/PT materialson May 3, 2026 at 11:25 am May 3, 2026 Publication date: 15 July 2026 Source: Clinica Chimica Acta, Volume 589 Author(s): Jie Zeng, Chunyan Teng, Haixia Li, Laisheng Li, Jun Xia, Lu Pang, Ziyi Zeng, Yufen Jin, Chumei Huang, …
Read more The diagnostic accuracy of synovial leukocyte esterase, glucose and calprotectin in diagnosing periprosthetic joint infectionon May 3, 2026 at 11:25 am May 3, 2026 Publication date: 15 July 2026 Source: Clinica Chimica Acta, Volume 589 Author(s): Mohammed Alkadhem, Karsten Ottink, Lucie Wagenmakers, Joris Ploegmakers, Paul Jutte, Anneke Muller Kobold, Marjan Wouthuyzen-Bakker
Longitudinal changes in fatty liver index, genetic susceptibility, and incident atrial fibrillationon May 3, 2026 at 11:25 am May 3, 2026 Publication date: 15 July 2026 Source: Clinica Chimica Acta, Volume 589 Author(s): Siyang Liu, Houde He, Hualan Chen, Hualin Duan, Ying Sun, Dan Deng, Zihao Gui, Lan Liu, Ningjian Wang, …
Read more Correction to: Creatinine Measurement in Pediatrics: Is There Still a Role for the Compensated Jaffe Method? April 30, 2026 Clin Chem. 2026 Apr 29:hvag040. doi: 10.1093/clinchem/hvag040. Online ahead of print. NO ABSTRACT PMID:42054146 | DOI:10.1093/clinchem/hvag040
Reply to “Biological variation of serum cholinesterase activity in healthy subjects”: analytical validation of cholinesterase activity measurement in routine practice: experience from a French clinical laboratoryPierre Mercieron April 29, 2026 at 10:00 am April 30, 2026 Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2026-0465. Online ahead of print. NO ABSTRACT PMID:42053521 | DOI:10.1515/cclm-2026-0465
No association between high plasma ionized calcium and minor neuropsychological symptoms in two general population cohortsCamilla J Kobyleckion April 29, 2026 at 10:00 am April 30, 2026 Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2025-1356. Online ahead of print. ABSTRACT OBJECTIVES: Hypercalcemia has been associated with various non-specific minor neuropsychological symptoms but mainly in patient cohorts. …
Read more Advancing the implementation of standardised reporting units for haemostasis factor assays through collaborative effortsStephen MacDonaldon April 29, 2026 at 10:00 am April 30, 2026 Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2026-0287. Online ahead of print. NO ABSTRACT PMID:42053189 | DOI:10.1515/cclm-2026-0287
Real-world performance of Lumipulse G plasma p-tau217: a six-month experience of a specialized clinical neurochemistry laboratoryBurak Arslanon April 29, 2026 at 10:00 am April 30, 2026 Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2026-0370. Online ahead of print. ABSTRACT OBJECTIVES: Plasma p-tau217 is a leading blood-based biomarker for Alzheimer’s disease (AD), offering high diagnostic accuracy …
Read more Large language models and statistical calculations: a cautionary noteMatteo Vidalion April 29, 2026 at 10:00 am April 30, 2026 Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2026-0409. Online ahead of print. NO ABSTRACT PMID:42054485 | DOI:10.1515/cclm-2026-0409
Clinical validation and implementation of mSTOP, a machine learning-based, longitudinal prediction model for the early identification of non-small cell lung cancer patients who not benefit from immune checkpoint inhibitor treatmentHuub H van Rossumon April 29, 2026 at 10:00 am April 30, 2026 Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2025-1624. Online ahead of print. ABSTRACT OBJECTIVES: There has been a lot of interest in the field of laboratory medicine regarding the …
Read more The landscape of clinical pathology and laboratory medicine education in Brazil: challenges and disparities across 180 medical schoolsDébora Maria Tavares de Andradeon April 29, 2026 at 10:00 am April 30, 2026 Clin Chem Lab Med. 2026 Apr 29. doi: 10.1515/cclm-2026-0559. Online ahead of print. NO ABSTRACT PMID:42054102 | DOI:10.1515/cclm-2026-0559
High-throughput UHPLC–MS/MS method for 15 protein-bound uremic toxins in human serumon April 30, 2026 at 11:32 am April 30, 2026 Publication date: 15 July 2026 Source: Clinica Chimica Acta, Volume 589 Author(s): Qiong Wu, Zhipeng Wan, Jinhua Lan, Xiuxiu Zhang, Linlang Huang, Bo Ji, Longhao Chen, Yang Sha, Zhiguo Pan, …
Read more Trimethyllysine as a potential biomarker for heart failureon April 30, 2026 at 11:32 am April 30, 2026 Publication date: 15 July 2026 Source: Clinica Chimica Acta, Volume 589 Author(s): Yuyan Lei, Qing Fang, Qingqi Wu, Guiling Xiong, Junyi Jiang, Yu Wu, Lulu Chen, Dongsheng Ouyang, Zhenyu Li, …
Read more Poor Performance of LDL-Cholesterol Equations versus Beta Quantification in a Very Large Cohort of Patients with Dyslipidemia April 29, 2026 Clin Chem. 2026 Apr 28:hvag038. doi: 10.1093/clinchem/hvag038. Online ahead of print. ABSTRACT BACKGROUND: Accurate estimations of low-density lipoprotein cholesterol (LDL-C) is important to guide clinical decisions concerning lipid-lowering treatment. The …
Read more Saliva vs Plasma in Liquid Biopsy Sampling for Head and Neck Cancer: A Comparative Study April 29, 2026 Clin Chem. 2026 Apr 28:hvag035. doi: 10.1093/clinchem/hvag035. Online ahead of print. ABSTRACT BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) presents significant diagnostic and therapeutic challenges due to its rising …
Read more Accuracy evaluation of calibrator value assignment in 25-hydroxyvitamin D LC-MS/MS assays: a metrological traceability-based studyHewei Sunon April 28, 2026 at 10:00 am April 29, 2026 Clin Chem Lab Med. 2026 Apr 27. doi: 10.1515/cclm-2026-0450. Online ahead of print. NO ABSTRACT PMID:42048535 | DOI:10.1515/cclm-2026-0450
Identification of prohibited substances in contaminated dietary supplements associated with adverse analytical findings in athletesPascal Kintzon April 28, 2026 at 10:00 am April 29, 2026 Clin Chem Lab Med. 2026 Apr 27. doi: 10.1515/cclm-2026-0566. Online ahead of print. NO ABSTRACT PMID:42048171 | DOI:10.1515/cclm-2026-0566
Post-transplant ring sideroblasts are common in haploidentical peripheral blood stem cell transplantation but not linked to SF3B1 mutationsMarlene Hollensteinon April 26, 2026 at 10:00 am April 29, 2026 Clin Chem Lab Med. 2026 Apr 22. doi: 10.1515/cclm-2026-0080. Online ahead of print. ABSTRACT OBJECTIVES: To determine the prevalence of erythroid dysplasia and ring sideroblasts (RS) after peripheral blood stem …
Read more Albumin-adjusted (“corrected”) calcium should no longer be reported: a position statement from the Joint IOF Working Group and IFCC Committee on Bone Metabolism and EFLM Committee on CKDEtienne Cavalieron April 26, 2026 at 10:00 am April 29, 2026 Clin Chem Lab Med. 2026 Apr 20. doi: 10.1515/cclm-2026-0545. Online ahead of print. NO ABSTRACT PMID:42035248 | DOI:10.1515/cclm-2026-0545
Reporting of pre-analytical variables affecting the determination of brain-derived neurotrophic factor (BDNF) in patients with stroke: a scoping reviewElisa Bevilacquaon April 25, 2026 at 10:00 am April 29, 2026 Clin Chem Lab Med. 2026 Apr 21. doi: 10.1515/cclm-2026-0277. Online ahead of print. ABSTRACT INTRODUCTION: Brain-derived neurotrophic factor (BDNF) is a neurotrophin expressed in the central nervous system, where it …
Read more 