Aberrantly glycosylated PSMA in urine as a potential marker for prostate canceron December 22, 2025 at 10:55 am December 22, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Misba Khan, Md. Khirul Islam, Pekka Taimen, Peter J. Boström, Urpo Lamminmäki, Janne Leivo
Myeloperoxidase as a Biomarker in COPDon December 22, 2025 at 10:55 am December 22, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): A. Rekha, Gaurav Gupta, Pareshkumar N. Patel, Shefali, G. PadmaPriya, Laxmidhar Maharana, Moayad Al Shahwan, Popat S. Kumbhar, …
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Recent advances in the early detection of ovarian Canceron December 22, 2025 at 10:55 am December 22, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Anahita Soleimani, Akbar Amirfiroozy, Mohammad M. Pourseif, Mahmoud Shekari Khaniani
Diagnostic performance of non-invasive markers for distinguishing MASLD/MASH: insights from meta-analysis and real-world dataon December 21, 2025 at 4:10 pm December 21, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Arti Patil, Suraj Bhausaheb Mungase, Mounika Nadella, Ramu Adela
Microfluidic biosensors and devices for brain tumor diagnosis and monitoringon December 21, 2025 at 4:10 pm December 21, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Omer Qutaiba B. Allela, Wadhah Hasan Alkhazali, Vimal Arora, Pallavi Prahlad, Biswaranjan Mohanty, Archana Dhyani, Shreeya Uppal, Mansur …
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Multi-omic biomarkers in premature ovarian insufficiencyon December 21, 2025 at 4:10 pm December 21, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Runzhuo Wu, Honghui Liu, Haiyan Zhang
Simple lithium measurement in capillary dried plasma microsamples collected with the HealthID PSD deviceon December 21, 2025 at 11:45 am December 21, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Eduarda Milena Reichert, Carolina Weber Ferrareze, Mayara Bernardes, Giovana Piva Peteffi, Amanda Pachedo Bondan, Mariele Feiffer Charão, Rafael Linden
Increased KIR + CD8+ T cell frequency with impaired cytotoxic potential in systemic lupus erythematosuson December 20, 2025 at 1:45 pm December 20, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Yun Wang, Xiaofang Bai, Ting Wang, Wei Wei, Rujia Chen, Renren Ouyang, Feng Wang, Hongyan Hou, Shiji Wu …
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Fecal Microbiota Therapy: Clinical Laboratory Testing and Metabolomic Approaches for Donor Screening, Product Assessment, and Patient Monitoring December 20, 2025 Clin Chem. 2025 Dec 19:hvaf156. doi: 10.1093/clinchem/hvaf156. Online ahead of print. ABSTRACT BACKGROUND: The safety and efficacy of fecal microbiota transplantation for prevention of recurrent Clostridioides difficile infection relies on …
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Global IVD: Barriers, Trends, and Future December 20, 2025 Clin Chem. 2025 Dec 19:hvaf184. doi: 10.1093/clinchem/hvaf184. Online ahead of print. NO ABSTRACT PMID:41417459 | DOI:10.1093/clinchem/hvaf184
Improving the environmental impact paradox of clinical medical laboratorieson December 19, 2025 at 3:59 pm December 19, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Pernilla Sörme, Scott Weitze
Establishing serum proprotein convertase Subtilisin/Kexin type 9 (PCSK9) reference intervalson December 19, 2025 at 12:53 pm December 19, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Rosaria Vincenza Giglio, Luisa Agnello, Anna Maria Ciaccio, Fabio Del Ben, Giuseppina Levantino, Francesca Ajello, Elisabetta Scirè, Marcello …
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Evaluating the use of unconcentrated urine for protein electrophoresis and immunofixation: An alternative approach for efficient analysis.on December 19, 2025 at 12:53 pm December 19, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Lokinendi.V. Rao, Salim E. Kabawat
Electrochemical biosensors for lactoferrinon December 19, 2025 at 12:53 pm December 19, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Sajad Alavimanesh, Asma Vafadar, Setayesh Jannati, Salamn M. Abd, Muyassar Norberdiyeva, Sajad Ehtiati, Amir Savardashtaki
Digital health integration in chronic kidney diseaseon December 19, 2025 at 12:53 pm December 19, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Ting Deng, Yi Xue, Nonglak Methakanjanasak
A novel fluorescent-labeled serum protein electrophoresis method for detection of monoclonal free light chains in serumon December 18, 2025 at 3:03 pm December 18, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Gaoyang Pang, Xiaojun Kang, Yan Li, Xiaojuan Zhang, Huijun Ren
Enhancing creatinine detection: Innovative biosensors for monitoring kidney functionon December 18, 2025 at 11:40 am December 18, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Mohammad Mahdi Heidari, Sepideh Shadravan, Samira Jafarisis, Shahab Masoumi, Shahla Shiri, Sajjad Jafarzadeh, Ahmad Mobed
Comparative analysis of three platforms for serum NfL quantification in healthy controls and MS patientsJustina Dargvainieneon December 17, 2025 at 11:00 am December 18, 2025 Clin Chem Lab Med. 2025 Dec 18. doi: 10.1515/cclm-2025-1476. Online ahead of print. ABSTRACT OBJECTIVES: Neurofilament light chain (NfL) is a biomarker of neuroaxonal damage in various neurological conditions, including …
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Development and validation of a candidate reference measurement procedure for free triiodothyronine and free thyroxine in human serum using equilibrium dialysis isotope-dilution liquid chromatography-tandem mass spectrometryMin Zhanon December 17, 2025 at 11:00 am December 18, 2025 Clin Chem Lab Med. 2025 Dec 18. doi: 10.1515/cclm-2025-0874. Online ahead of print. ABSTRACT OBJECTIVES: Free triiodothyronine (FT3) and free thyroxine (FT4) are important diagnostic markers for assessing thyroid function. …
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Response to Lenters-Westra, Erna, et al. “Limitations of glycated albumin standardization when applied to the assessment of diabetes patients” Clin Chem Lab Med doi.org/10.1515/cclm-2024-0591Julie Sherfanon December 17, 2025 at 11:00 am December 18, 2025 Clin Chem Lab Med. 2025 Dec 18. doi: 10.1515/cclm-2025-1560. Online ahead of print. NO ABSTRACT PMID:41405966 | DOI:10.1515/cclm-2025-1560
Comparative Evaluation of Two Different Blood Collection Tubes For Hematological and Biochemical Testingon December 17, 2025 at 3:53 pm December 17, 2025 Publication date: Available online 16 December 2025 Source: Practical Laboratory Medicine Author(s): Michela Salvatici, Francesca Carreras, Monica Gaimarri, Francesca Delia Sansico, Paolo Marinoni, Chiara Masserini, Barbara Bianchi, Carmen Sommese, Lorenzo …
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Association of Serum Uromodulin and Carbamylated Albumin with All-Cause and Cardiovascular Mortality in Patients with No or Mild Chronic Kidney Disease December 16, 2025 Clin Chem. 2025 Dec 16:hvaf166. doi: 10.1093/clinchem/hvaf166. Online ahead of print. ABSTRACT BACKGROUND: Serum uromodulin (SUmod) and carbamylated albumin (C-Alb) are emerging biomarkers for chronic kidney disease (CKD) progression and …
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Improving Recognition of Secondary Hemophagocytic Lymphohistiocytosis (HLH) through a Ferritin-Based Automated Alert: An Interrupted Time Series Analysis December 16, 2025 Clin Chem. 2025 Dec 16:hvaf170. doi: 10.1093/clinchem/hvaf170. Online ahead of print. NO ABSTRACT PMID:41400225 | DOI:10.1093/clinchem/hvaf170
Serial measurements of neuron specific enolase, glial fibrillary acidic protein and neurofilament light for mortality prediction in patients with severe acute brain injury in the ICUWolmet E Haksteenon December 16, 2025 at 11:00 am December 16, 2025 Clin Chem Lab Med. 2025 Dec 17. doi: 10.1515/cclm-2025-1315. Online ahead of print. ABSTRACT OBJECTIVES: Prognostication in patients with severe acute brain injury (SABI) in the Intensive Care Unit (ICU) …
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Artificial intelligence and machine learning in thrombosis and hemostasis: a scoping review of clinical and laboratory applications, challenges, and future directionsMohammad A Altememion December 16, 2025 at 11:00 am December 16, 2025 Clin Chem Lab Med. 2025 Dec 17. doi: 10.1515/cclm-2025-1450. Online ahead of print. ABSTRACT This scoping review followed the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for …
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Defining non-diabetic hypoglycemia: is there an appropriate plasma glucose threshold?Tomás González-Vidalon December 16, 2025 at 11:00 am December 16, 2025 Clin Chem Lab Med. 2025 Dec 17. doi: 10.1515/cclm-2025-1496. Online ahead of print. NO ABSTRACT PMID:41400589 | DOI:10.1515/cclm-2025-1496
Hook effect for ferritin immunoassays: implications for clinical practiceMeshach Asare-Wereheneon December 16, 2025 at 11:00 am December 16, 2025 Clin Chem Lab Med. 2025 Dec 17. doi: 10.1515/cclm-2025-1277. Online ahead of print. NO ABSTRACT PMID:41400556 | DOI:10.1515/cclm-2025-1277
Non-invasive biological matrices on biosensor designon December 16, 2025 at 2:09 pm December 16, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Ghada Al-Assi, Waleed K. Abdulsahib, Sanan Thaer Abdal-Wahab, G. Padma Priya, Subhashree Ray, Sindu Divakaran, Gunjan Mukherjee, Ashish …
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Toward neonatal analytical stewardship: building on Cadamuro et al.’s minimum-volume frameworkMulavagili Vijayasimhaon December 15, 2025 at 11:00 am December 16, 2025 Clin Chem Lab Med. 2025 Dec 16. doi: 10.1515/cclm-2025-1557. Online ahead of print. NO ABSTRACT PMID:41397217 | DOI:10.1515/cclm-2025-1557
Quantitative analysis of phylloquinone (vitamin K1) and menaquinone (vitamin K2) in serum of Russians by liquid chromatography-tandem mass spectrometryMikhail Vokuevon December 15, 2025 at 11:00 am December 16, 2025 Clin Chem Lab Med. 2025 Dec 16. doi: 10.1515/cclm-2025-0719. Online ahead of print. ABSTRACT OBJECTIVES: Vitamin K homologues are essential to human health, and their concentrations in biological samples serve …
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Hyperferritinemia and analytical challenges: can proteomics make the difference?Victor Corasolla Carregarion December 15, 2025 at 11:00 am December 15, 2025 Clin Chem Lab Med. 2025 Dec 16. doi: 10.1515/cclm-2025-1616. Online ahead of print. NO ABSTRACT PMID:41396073 | DOI:10.1515/cclm-2025-1616
Assessment of the stability of 20 biochemical analytes in serum and whole blood samples after storage at nonstandard temperatureson December 15, 2025 at 12:10 pm December 15, 2025 Publication date: Available online 15 December 2025 Source: Practical Laboratory Medicine Author(s): Gabriella Iacovetti, Bradley B. Collier, Jill M. Rafalko, Mitchell Peevler, Nicolas Tokunaga, Jason Ragar, Whitney Brandon, Matthew R. …
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Electrochemical MicroRNA biosensors for kidney Cancer: From biomarker discovery to point-of-care diagnosticson December 14, 2025 at 11:25 am December 14, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Sadegh Zarei, Seyed Morteza Hosseiniara, Solmaz Sadat Hosseini Zijoud, Reza Hosseiniara
Clinical evaluation of a sensitive fluorescent PCR assay for trichomonas vaginalison December 13, 2025 at 3:59 pm December 13, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Tao Jiang, Jinbo Yang, Bo Nie, Jiaqi Peng, Limin Zhou, Hao Wu, Xianying Chen, Jie Chen, Xuan Tang, …
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The double-edged role of point-of-care testing in modern medicineon December 13, 2025 at 3:59 pm December 13, 2025 Publication date: 15 February 2026 Source: Clinica Chimica Acta, Volume 582 Author(s): Tahir S. Pillay, Ashlin Rampul, Evette L. Subramoney, Barbara S. van Deventer, Chantal van Niekerk, Siphokazi Gwiliza
The democratization of cancer screening, or a waste of valuable resources?Miyo K Chatanakaon December 12, 2025 at 11:00 am December 13, 2025 Clin Chem Lab Med. 2025 Dec 15. doi: 10.1515/cclm-2025-1434. Online ahead of print. ABSTRACT The discovery of circulating tumor DNA (ctDNA) prompted many scientists and companies to apply this new …
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The Analytical Performance of Neonatal Total Bilirubin Assays Does Not Meet the Clinical Need December 12, 2025 Clin Chem. 2025 Dec 12:hvaf175. doi: 10.1093/clinchem/hvaf175. Online ahead of print. NO ABSTRACT PMID:41385263 | DOI:10.1093/clinchem/hvaf175
Novel and known fibrinogen gene mutations in Chinese pediatric patients with congenital dysfibrinogenemia: genetic and functional characterizationon December 12, 2025 at 7:44 pm December 12, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Juan Huang, Duocai Wang, Ying Wang, Yongqiang Yang, Dong Peng, Meizhu Luo, Xiaoying Fu
Circular RNA biomarkers in acute myeloid leukemiaon December 12, 2025 at 2:23 pm December 12, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Hossein Gandomkar, Ehsan Maghrebi-Ghojogh, Danyal Daneshdoust, Sarah Qutayba Badraldin, Ali Fawzi Al-Hussainy, Rasim M. Salih, Mohaned Adil, Samaneh …
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Cortisol measurement challenges in managing ectopic Cushing’s syndrome with etomidatePauline Brouwerson December 11, 2025 at 11:00 am December 12, 2025 Clin Chem Lab Med. 2025 Dec 15. doi: 10.1515/cclm-2025-1211. Online ahead of print. NO ABSTRACT PMID:41380673 | DOI:10.1515/cclm-2025-1211
The indispensable role of phenotypic screening in thalassemia diagnosis: a case of deception uncovered by inconsistent resultsYouqiong Lion December 11, 2025 at 11:00 am December 12, 2025 Clin Chem Lab Med. 2025 Dec 15. doi: 10.1515/cclm-2025-1521. Online ahead of print. NO ABSTRACT PMID:41380660 | DOI:10.1515/cclm-2025-1521
Prognostic value of suPAR in sepsis: a potential tool to support patient management in the Emergency DepartmentSimone Leggerion December 11, 2025 at 11:00 am December 12, 2025 Clin Chem Lab Med. 2025 Dec 15. doi: 10.1515/cclm-2025-1299. Online ahead of print. ABSTRACT OBJECTIVES: The soluble urokinase plasminogen activator receptor (suPAR) is a well-established biomarker of immune activation, reflecting …
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Effect of blood acidification on hemolysis-induced insulin degradationon December 11, 2025 at 1:09 pm December 11, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Şerif Ercan
Integrating CRISPR with SERS: Toward intelligent point-of-care diagnostics of the futureon December 11, 2025 at 1:09 pm December 11, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Biqing Chen, Jiayin Gao, Haizhu Sun, Yinghan Zhao, Yan Liu, Xiaohong Qiu, Yang Li
Extreme hypokalemia in an asymptomatic 40-year-old cachectic maleon December 11, 2025 at 12:07 pm December 11, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Stanislas Francois, Sreekanth Rajagopal, Anne Boutten, Alexandre Raynor, Katell Peoc’h
Mass spectrometry reveals limitations of serum immunofixation electrophoresis in monitoring lambda light chain myelomaYu Chenon December 10, 2025 at 11:00 am December 10, 2025 Clin Chem Lab Med. 2025 Dec 11. doi: 10.1515/cclm-2025-1337. Online ahead of print. NO ABSTRACT PMID:41369217 | DOI:10.1515/cclm-2025-1337
Shift happens: the utility of external quality assessment data in evaluating folate lot changesRachel Marringtonon December 10, 2025 at 11:00 am December 10, 2025 Clin Chem Lab Med. 2025 Dec 11. doi: 10.1515/cclm-2025-1569. Online ahead of print. NO ABSTRACT PMID:41369135 | DOI:10.1515/cclm-2025-1569
Comparability of venous and capillary blood measurements for a host-protein test differentiating bacterial from viral infectionson December 10, 2025 at 10:45 am December 10, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Mary Hainrichson, Nitzan Shamir, Naftalie Senderovich, May Levin, Husein Darawsha, Ayelet Raz, Salim Halabi, Oded Shaham, Roy Navon, Tanya M. …
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Rapid identification and quantification of residual daratumumab in multiple myeloma patients by MALDI – TOF mass spectrometryon December 10, 2025 at 10:45 am December 10, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Hou-Long Luo, Huan Ding, Fan Chen, Yuxi Wang, Lin Zhou, Peng Ye, Hui Yu, Shangying Wu, Weijie Xie, …
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HOX genes and tumor metastasis: epigenetic regulatory mechanismson December 10, 2025 at 10:45 am December 10, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Junwei Li, Jinhua Yan, Shubing Zhang
Galectin-3 as a cardiac biomarkeron December 10, 2025 at 10:45 am December 10, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Asif Ahmad Bhat, Yahia Alghazwani, Kumarappan Chidambaram, M.M. Rekha, Samir Sahoo, Pavan Goud, Nadeem Sayyed, Vikas Jakhmola, Moyad …
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Evaluation of three NT-proBNP assays for heart failureon December 10, 2025 at 10:45 am December 10, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): Isaiah K. Mensah, Brittany Roemmich, Sydny Lawless, Alexis Wysocki, David Daghfal, Christian J. Hunter, Christopher W. Farnsworth
Impact of an autonomous delivery robot on sample turnaround time in a clinical laboratory: an early evaluation of first implementationJacopo Gervasonion December 9, 2025 at 11:00 am December 9, 2025 Clin Chem Lab Med. 2025 Dec 10. doi: 10.1515/cclm-2025-1336. Online ahead of print. ABSTRACT OBJECTIVES: The aim of this study was to evaluate the impact of introducing an autonomous courier …
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A specific-neonatal hemolysis correction model for accurate potassium assessment in blood samples with in vitro hemolysisJinmei Lion December 9, 2025 at 11:00 am December 9, 2025 Clin Chem Lab Med. 2025 Dec 10. doi: 10.1515/cclm-2025-1484. Online ahead of print. ABSTRACT OBJECTIVES: Accurate determination of blood potassium levels in neonates presents significant clinical challenges, primarily attributable to …
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The European Health Data Space: challenges and opportunities for laboratory medicinePieter Vermeerschon December 9, 2025 at 11:00 am December 9, 2025 Clin Chem Lab Med. 2025 Dec 10. doi: 10.1515/cclm-2025-1618. Online ahead of print. NO ABSTRACT PMID:41364080 | DOI:10.1515/cclm-2025-1618
Commutability assessment of NIST SRM 3666 albumin and creatinine in frozen human urine among routine clinical laboratory measurement procedureson December 9, 2025 at 3:22 pm December 9, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Ashley Beasley-Green, Johanna E. Camara, Elena S.C. Wood, N. Alan Heckert, W. Greg Miller, Lorin M. Bachmann, Laura …
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FTIR spectroscopy of plasma exosomes reveals distinct lipidomic and proteomic signatures for early Alzheimer’s disease detectionon December 9, 2025 at 3:22 pm December 9, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Rishabh Singh, Abhay Mishra, Vipin Kumar, Anu Gupta, Sadaqa Zehra, Neerja Rani, Renu Dhingra, Gyan Prakash Modi, Krishna …
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qPCR-melting curve analysis in molecular diagnosticson December 9, 2025 at 3:22 pm December 9, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Li He, Nanqiu Peng, Zihan Ran, Xiaoshan Rong, Zhenghu Chen
Aptasensors in colorectal Cancer: Emerging tools for precision diagnosticson December 9, 2025 at 3:22 pm December 9, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Qamar Abuhassan, Ali M. Atoom, R. Roopashree, Jaya Bhanu Kanwar, T. Sudhakar, Vipasha Sharma, Ashish Singh Chauhan, Oybek …
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Ovarian cancer biosensors: established glycoproteins to emerging molecular biomarkerson December 8, 2025 at 1:31 pm December 8, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Yalda Jahanbani, Farzaneh Fathi, Hosein azizi, Parvin Bastani, Faride Ranjbari
Multi-omic biomarker detection in ovarian canceron December 8, 2025 at 1:31 pm December 8, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Qamar Abuhassan, Ghada Al-Assi, M.M. Rekha, Kabita Chanania, M. Bavanilatha, Vimal Arora, Aashna Sinha, Mehrigul Hayitova
Urinary exosomes: Emerging biomarkers for urinary tract infectionon December 8, 2025 at 1:31 pm December 8, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Narbaev Zafar, Umurzoqov Dilmurod, Islom Kadirov, Eshchanova Gulbakhor, Sidikov Akmal, Gulomova Gulnora, Sharipov Rustam, Tadjibaeva Muyassar Karimbaevna, Ravshan …
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Response to: Shift happens: The utility of external quality assessment data in evaluating folate lot changes. https://doi.org/10.1515/cclm-2025-1569Anders Larssonon December 6, 2025 at 11:00 am December 6, 2025 Clin Chem Lab Med. 2025 Dec 8. doi: 10.1515/cclm-2025-1575. Online ahead of print. NO ABSTRACT PMID:41351029 | DOI:10.1515/cclm-2025-1575
Matrix commutability for ApoA1, ApoB, and lipoprotein(a) testing: Comparison between serum and heparinized plasmaon December 6, 2025 at 9:23 am December 6, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Meryem Benamour, Hadrien Cools, Yasmine Boufelliga, Catherine Fillée, Damien Gruson
Evaluation of a novel host protein-based assay for ruling out bacterial infections in patients with suspected respiratory tract infections at an urban academic hospitalon December 6, 2025 at 9:23 am December 6, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Yaxin Li, David Bodnar, Hnin Ingyin, Samantha Maniccia, Zhen Zhao, He S. Yang
Evaluation of iMS-IP assay for the detection and typing of monoclonal immunoglobulinson December 5, 2025 at 2:18 pm December 5, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Yu Chen, Liangshun You, Li Zhu, Xuejiao Yin, Qiumei Yao, Shengnan Ding, Jiaying Ge, Yi Liu, Hongyan Tong, …
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Blood Cell Agglutination Interference in Complete Blood Count Analysis December 4, 2025 Clin Chem. 2025 Jun 3;71(6):629-631. doi: 10.1093/clinchem/hvae218. NO ABSTRACT PMID:41342347 | DOI:10.1093/clinchem/hvae218
Breaking Barriers in Biosensing: Real-Time Continuous Protein Detection in Interstitial Fluid December 4, 2025 Clin Chem. 2025 Jun 3;71(6):723-724. doi: 10.1093/clinchem/hvaf033. NO ABSTRACT PMID:41342350 | DOI:10.1093/clinchem/hvaf033
Commentary on Blood Cell Agglutination Interference in Complete Blood Count Analysis December 4, 2025 Clin Chem. 2025 Jun 3;71(6):632-633. doi: 10.1093/clinchem/hvaf008. NO ABSTRACT PMID:41342349 | DOI:10.1093/clinchem/hvaf008
Commentary on Blood Cell Agglutination Interference in Complete Blood Count Analysis December 4, 2025 Clin Chem. 2025 Jun 3;71(6):631-632. doi: 10.1093/clinchem/hvaf007. NO ABSTRACT PMID:41342348 | DOI:10.1093/clinchem/hvaf007
Fragmentation patterns of pathogen-derived cell-free DNA as a promising non-invasive biomarker for bloodstream infection diagnosison December 4, 2025 at 11:53 am December 4, 2025 Publication date: December 2025 Source: Practical Laboratory Medicine, Volume 47 Author(s): Qichuan Fu, Jie Wang, Liya Yue, Tianyu Lu, Wenyu Shi, Cuidan Li, Xiaoyuan Jiang, Peihan Wang, Fei Chen
Liquid chromatography-mass spectrometry quantitation and prevalence of medetomidine and xylazine in New Haven, Connecticuton December 4, 2025 at 11:53 am December 4, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Jillian Kodger, Gina Cassella-McLane, Mallorie Iozzo, Joe M. El-Khoury
One‑carbon pathway gene expression analyses in blood samples of subjects with trisomy 21on December 4, 2025 at 11:53 am December 4, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Beatrice Vione, Alessandro Maria Gaudesi, Francesca Antonaros, Michela Cicilloni, Lorenza Vitale, Allison Piovesan, Maria Chiara Pelleri, Pierluigi Strippoli, …
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PREEMPT’ing Overreliance on Peripheral Blood-Based ColoRectal Cancer Screening December 4, 2025 Clin Chem. 2025 Dec 3:hvaf137. doi: 10.1093/clinchem/hvaf137. Online ahead of print. NO ABSTRACT PMID:41335517 | DOI:10.1093/clinchem/hvaf137
Pre-Exposure Prophylaxis (PrEP)-Associated HIV Monitoring and Self-Testing December 4, 2025 Clin Chem. 2025 Dec 3:hvaf155. doi: 10.1093/clinchem/hvaf155. Online ahead of print. ABSTRACT BACKGROUND: Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) encompasses the use of antiviral medications to prevent HIV acquisition …
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Phosphorylated Tau in Developing and Degenerating Brains: A 30-Year-Old Puzzle Revisited December 4, 2025 Clin Chem. 2025 Dec 3:hvaf161. doi: 10.1093/clinchem/hvaf161. Online ahead of print. NO ABSTRACT PMID:41335514 | DOI:10.1093/clinchem/hvaf161
Diagnostic accuracy of non-coding RNA for detecting endometriosis: A systematic review and meta-analysison December 3, 2025 at 9:31 am December 3, 2025 Publication date: 1 February 2026 Source: Clinica Chimica Acta, Volume 581 Author(s): Seyed Danial Mohammadi, Abasali Keshtkar, Ashraf Moini, Tayebeh Rastegar, Faezeh Heydarikhah, Anahid Shafie, Mohammadreza Ghasemi, Hojat Ghasemnejad Berenji …
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Clinical laboratory testing of blood from patients presenting to the emergency department with acute bleeding due to factor Xa inhibitors: An unmet medical needon December 3, 2025 at 9:31 am December 3, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Alan H.B. Wu, W. Franklin Peacock
Clinical assessment and acceptance criteria for continuous glucose monitoring (CGM) system performance: A proposed guideline by the IFCC Working Group on CGMon December 3, 2025 at 9:31 am December 3, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Stefan Pleus, Manuel Eichenlaub, Pradeep Kumar Dabla, Peter Diem, Elisabet Eriksson Boija, Marion Fokkert, Rolf Hinzmann, Johan Jendle, …
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Aberrant Plasma Cells in the Absence of M-Protein: Ancillary Testing beyond Protein Electrophoresis December 2, 2025 Clin Chem. 2025 Dec 2;71(12):1195-1199. doi: 10.1093/clinchem/hvaf097. NO ABSTRACT PMID:41329021 | DOI:10.1093/clinchem/hvaf097
Commentary on Aberrant Plasma Cells in the Absence of M-protein: Ancillary Testing beyond Protein Electrophoresis December 2, 2025 Clin Chem. 2025 Dec 2;71(12):1200. doi: 10.1093/clinchem/hvaf117. NO ABSTRACT PMID:41329020 | DOI:10.1093/clinchem/hvaf117
Commentary on Aberrant Plasma Cells in the Absence of M-Protein: Ancillary Testing beyond Protein Electrophoresis December 2, 2025 Clin Chem. 2025 Dec 2;71(12):1201. doi: 10.1093/clinchem/hvaf130. NO ABSTRACT PMID:41329019 | DOI:10.1093/clinchem/hvaf130
Transdermal GFR Signals a New Horizon in Renal Diagnostics December 2, 2025 Clin Chem. 2025 Dec 2;71(12):1281-1282. doi: 10.1093/clinchem/hvaf106. NO ABSTRACT PMID:41329018 | DOI:10.1093/clinchem/hvaf106
Extended verification of an automated MALDI-TOF mass spectrometry system for high throughput serum M-protein measurementLouis Nevejanon December 2, 2025 at 11:00 am December 2, 2025 Clin Chem Lab Med. 2025 Dec 3. doi: 10.1515/cclm-2025-0894. Online ahead of print. ABSTRACT OBJECTIVES: This study aimed to perform an extended analytical verification of the Immunoglobulin Isotypes (GAM) for …
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Impact of Clinical Variables on cfDNA Fragmentomic Signatures and Their Potential as Confounders in Cancer Detection December 2, 2025 Clin Chem. 2025 Dec 2:hvaf163. doi: 10.1093/clinchem/hvaf163. Online ahead of print. ABSTRACT BACKGROUND: Circulating cell-free DNA (cfDNA) fragmentomic features, such as fragment size and end motifs, have emerged as promising …
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Volatile organic compound signatures in breast cancer: A pilot study on cell-based detectionon December 2, 2025 at 2:12 pm December 2, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Ana J. Tenorio-Salazar, Fernanda M. Orduña-Medina, Boris Mizaikoff, Jan Mitrovics, Lorena Díaz de León-Martínez, Luz E. Alcántara-Quintana
Identification of lncRNA ZNF252P-AS1 as a novel diagnostic and prognostic biomarker for breast cancer patients: An integrated bioinformatics and experimental analysison December 2, 2025 at 2:12 pm December 2, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Nahla E. El-Ashmawy, Mariam A. Abo-Saif, Sara M. Hamouda, Eman G. Khedr
Unveiling regional patterns of IgE sensitization to peanut, hazelnut, and walnut in Italy: a nationwide bottom-up molecular surveyon December 2, 2025 at 2:12 pm December 2, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Giulia Marcassa, Danilo Villalta, Valeria Villella, Simonetta Friso, Maria Barrale, Ignazio Brusca, Enrico Scala
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of progesterone in human serum and plasmaSara Cheikh Ibrahimon December 1, 2025 at 11:00 am December 1, 2025 Clin Chem Lab Med. 2025 Dec 1. doi: 10.1515/cclm-2025-0514. Online ahead of print. ABSTRACT OBJECTIVES: Progesterone regulates reproductive processes and is used clinically to monitor ovarian function in people experiencing …
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Reducing inappropriate vitamin D testing: an analysis of three sequential diagnostic stewardship interventions and the carbon footprint implicationson November 29, 2025 at 3:43 pm November 29, 2025 Publication date: January 2026 Source: Clinical Biochemistry, Volume 141 Author(s): C. Hughes, M.A. Myers, M. Tickell-Painter, M. Aitchison, L. Roberts, R.J. Shorten
Serum placental growth factor: Pre-analytical stability, comparison of blood derivates and interference from biotin and hemolysison November 29, 2025 at 12:40 pm November 29, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Mette Tiedemann Skipper, Tina Parkner, Henriette Ladegård Skov, Cindy Soendersoe Knudsen
Evaluation of the commutability of lombardy region EQA control materials for enzymes, calcium, and creatinineon November 29, 2025 at 12:40 pm November 29, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Anna Carobene, Matteo Vidali, Ferruccio Ceriotti, Antonella Alberghini, Adele Arcangeli, Walter Bellandi, Paola Cappelletti, Lorenzo Cerutti, Alice Cotellessa, …
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An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of dehydroepiandrosterone sulfate in human serum and plasmaSara Cheikh Ibrahimon November 29, 2025 at 11:00 am November 29, 2025 Clin Chem Lab Med. 2025 Dec 1. doi: 10.1515/cclm-2025-0179. Online ahead of print. ABSTRACT OBJECTIVES: Dehydroepiandrosterone sulfate (DHEAS), the sulfate ester of dehydroepiandrosterone, is one of the most common steroid …
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The hook effect of an immunoassay results in a series of pediatric patients with elevated total immunoglobulin E: implications for dilution protocols and method comparisonOleg Melnichukon November 29, 2025 at 11:00 am November 29, 2025 Clin Chem Lab Med. 2025 Dec 1. doi: 10.1515/cclm-2025-1492. Online ahead of print. NO ABSTRACT PMID:41316679 | DOI:10.1515/cclm-2025-1492
Altered PCSK9 plasma levels after preeclampsia in the PERLA-Brazil studyon November 28, 2025 at 5:41 pm November 28, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Isabella Macedo Costa, Thaíse Emilia Moreira da Silva, Letícia Gonçalves Silva, Ana Paula Silva Ferreira, Thays Santos da …
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From conventional to personalized reference intervals and decision limits: addressing latent errors in the post-post analytical phaseAbdurrahman Coskunon November 27, 2025 at 11:00 am November 27, 2025 Clin Chem Lab Med. 2025 Nov 28. doi: 10.1515/cclm-2025-1338. Online ahead of print. ABSTRACT Laboratory errors are an important component of medical errors and are predominantly associated with the extra-analytical …
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Immunofixation electrophoresis image interpretation using transfer learning methodon November 27, 2025 at 1:50 pm November 27, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Berrin Oztas, Irfan Kosesoy
Attention-based deep learning for immunoglobulin typing from electrophoresis and laboratory dataon November 27, 2025 at 1:50 pm November 27, 2025 Publication date: 30 January 2026 Source: Clinica Chimica Acta, Volume 580 Author(s): Long Zhao, Ruihua Liu, Tian Zhang, Weiqing Song, Ning Song
Annual meeting of the Royal Belgian Society of Laboratory Medicine (RBSLM): “Beyond the Surface – Clinical biology of the apparently healthy individual”on November 27, 2025 at 11:00 am November 27, 2025 Clin Chem Lab Med. 2025 Nov 27. doi: 10.1515/cclm-2025-1532. Online ahead of print. NO ABSTRACT PMID:41305926 | DOI:10.1515/cclm-2025-1532
Addressing the silent epidemic of recreational nitrous oxide use: a position, call to action and recommendations by the European Federation of Clinical Chemistry and Laboratory Medicine Committee on Biological Markers of Nitrous Oxide AbuseGuillaume Grzychon November 26, 2025 at 11:00 am November 26, 2025 Clin Chem Lab Med. 2025 Nov 20. doi: 10.1515/cclm-2025-1060. Online ahead of print. ABSTRACT Recreational nitrous oxide (N2O) use has emerged as a growing public health concern, with increasing reports …
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